Abstract
Na+/Ca2+ exchangers (NCX) are membrane proteins that use the electrochemical gradient of Na+ to remove Ca2+ from the cytosol. They are essential for the maintenance of the intracellular Ca2+ homeostasis in various cell types, especially in excitable cells. CALX, the Na+/Ca2+ exchanger from Drosophila melanogaster, is found in sensory neuronal cells. It displays a unique regulatory behavio…