CV Lattes
ResearcherID
ORCID
Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Farmácia Bioquímica from Universidade de São Paulo (1975), graduate at Farmácia from Universidade de São Paulo (1974), master's at Biochemistry from Universidade de São Paulo (1980) and PhD. at Biochemistry from Universidade de São Paulo (1985). Has experience in Biochemistry, focusing on Biochemistry, acting on the following subjects:, snake venoms of genus Bothrops and Crotalus, tabernaemontana catharinensis, tityus serrulatus and scorpion venom. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
The purification of active components from venoms with high purity and in relatively high amounts is a limiting factor for the success of this project, since these active molecules are the object of study of all the proposed tests, aiming at obtaining compounds with biotechnological potential. Prominence chromatography system is a modern equipment and meets all requirements for the isolat…
The automatic sequencer of proteins/peptides is an equipment whose function is to identify the amino acids which comprise the primary structure of proteins and peptides. This identification occurs through the N-terminal region of the protein by Edman degradation and identification of PTH-amino acids. It is an essential equipment for laboratories working with identification and biochemical…
The equipment is a capillary electrophoresis platform for proteins and nucleic acids, and will be used for quantification and determination of the molecular weight of proteins (14kDa to 200 kDa), to determine the purity profile, glycosylation profile, and the purity and fragmentation of antibodies, as well as the separation and quantification of DNA and RNA. The advanced technology of thi…
Animal venoms constitute a rich source of pharmacologically active substances. Such molecules, named toxins, act either isolated or in synergy through the binding to cell receptors and/or interfering metabolic pathways fundamental to cell viability, inducing local, systemic and even lethal damage to the victim or pray. Exploring the mechanisms of action of toxins has been relevant for pro…
(Only some records are available in English at this moment)
Leukemia is a malignant disease of white blood cells, usually of unknown origin, whose main characteristic is the accumulation of abnormal young cells in the bone marrow, which replace normal blood cells. To evaluate new alternative therapies for the treatment of this disease, that affects thousands of individuals every year, this research project aims to evaluate the antitumor activity o…
Snake venoms are complex mixtures of biologically active compounds, among these, the peptides, still little explored. Shaped by evolutionary processes, these peptides are characterized by presenting diverse structures with a high degree of selectivity, what became them important candidates for models of the development of new drugs and biological tools. Therefore, the present study propos…
Sepsis, or generalized infection, is a syndrome characterized by a series of serious manifestations throughout the body caused by infections, pathogens such bacterias (gram-positive or gram-negatives) and fungi. Among the main bacterial components responsible for triggering inflammation in sepsis, we can mention the lipopolysaccharide (LPS). This bacterial membrane molecule is responsible…
(Only some records are available in English at this moment)
Snakebites are considered a health problem in most tropical countries and Bothrops genus is major cause of accidents in Brazil. Bothrops moojeni belongs to the Viperidae family, popularly known as "caiçara" or "jararacão" and is found in the Midwest and Southeast of Brazil. The accident is characterized by proteolytic (or necrotizing), coagulant and hemorrhagic activities. The snake veno…
| 2 / 2 | Ongoing research grants |
| 18 / 4 | Completed research grants |
| 30 / 18 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 51 / 25 | All research grants and scholarships |
| Associated processes | |