graduate at Ciências from Pontifícia Universidade Católica de Minas Gerais (1985), graduate at Medicina Veterinária from Universidade Federal de Minas Gerais (1993), master's at Physiology from Universidade Federal de Minas Gerais (1996) and ph.d. at Biochemistry from Universidade Federal de São Paulo (2000). Has experience in Byophysics, focusing on Byophysics, acting on the following subjects: cininas, animais transgênicos, calicreína, inflamação and pressão arterial. (Source: Lattes Curriculum)
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Kallikrein-kinin system (KKS) participates in inflammatory processes, pain mediation and control of blood pressure. Recent evidences suggest the involvement of this system in the modulation of physical exercise, metabolism and obesity. Such involvement could be partly mediated by interaction with the immune system, with glycemic control and cardiovascular homeostasis. To evaluate the role…
The kallikrein-kinin system (KKS) participates in inflammatory processes, pain mediation and control of blood pressure. Recent evidences suggest the involvement of this system in the modulation of physical exercise, metabolism and obesity. Such involvement could be partly mediated by interaction with the immune system, with glycemic control and cardiovascular homeostasis. To evaluate the …
Epidemiological and experimental studies with animals suggested that the first nutritional experiences of an individual; i.e., any uterine nutritional alteration, may affect the susceptibility of the fetus to develop chronic diseases related to the Metabolic Syndrome when adult, as obesity, hypertension, cardiovascular disease and Type 2 diabetes. This process is known as metabolic imprin…
The kallikrein-kinin system (KKS) participates in inflammatory processes, pain mediation and control of blood pressure. Recent evidences suggest the involvement of this system in the modulation of physical exercise, metabolism and obesity. Such involvement could be partly mediated by interaction with the immune system, with glycemic control and cardiovascular homeostasis. To evaluate the …
The increased prevalence of childhood obesity is alarming and epidemiological studies have suggested that early nutritional experiences may affect susceptibility to chronic diseases in adulthood, such as obesity, hypertension, cardiovascular disease and Type 2 diabetes and it is named metabolic programming. Changes in the fetal period may cause changes in lean body mass, endocrine, and va…
(Only some records are available in English at this moment)
Clinical and experimental studies have consistently demonstrated that low birth weight may contribute to the late development of cardiovascular disease. Although the factors involved in this effect have not yet been fully elucidated, changes such as reduced vascular compliance, incomplete vasculogenesis characterized by microvascular rarefaction and alteration of the endothelial cell modu…
Evidence indicates that the incidence of acute kidney injury (AKI) is increasing rapidly, particularly among patients hospitalized with other acute diseases and those undergoing major surgeries. The sequelae are severe and are characterized by an increased risk of short- and long-term mortality. Although mortality associated with AKI is declining, it remains unacceptably high. This decrea…
Kinins are involved in various aspects related to metabolism, such as glycemic, hepatic as well as in adipose tissue. Several studies have shown that the kinin B2 receptor is involved in the uptake of glucose, via GLUT4 translocation, via the insulin-independent route. This effect is probably due to an increase in intracellular calcium. On the other hand, we observed that kinin receptors …
(Only some records are available in English at this moment)
The glucose metabolism is closely related to an impairment of several chronic diseases, as obesity, diabetes and the metabolic syndrome. Kallikrein-kinin system (KKS) has been involved in different metabolic processes, demonstrated by knockout mice that are resistant to obesity. The kinin receptors, B1 (B1R) and B2 (B2R) are responsible for mediating the biological responses from the prec…
| 2 / 2 | Ongoing research grants |
| 13 / 8 | Completed research grants |
| 20 / 10 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 36 / 21 | All research grants and scholarships |
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CV Lattes
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