CV Lattes
ResearcherID
ORCID
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduate at Medicina from Universidade de São Paulo (1988), master's at Parasitologia from Universidade de São Paulo (1993) and ph.d. at Parasitologia from Universidade de São Paulo (1997). Has experience in Parasitology, focusing on Human Parasite Protozoology, acting on the following subjects: malaria, plasmodium falciparum, epidemiologia, diversidade antigenica and genetica de populacoes. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| Una ciudad convertida en laboratorio |
| A town turned laboratory |
| The uncertainty of herd immunity |
| La incertidumbre acerca de la inmunidad colectiva |
| A versatile parasite |
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
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| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Drug resistance has been for more than a century the hallmark of Plasmodium falciparum. This capacity has driven its expansion worldwide, in particular during the long period of established chloroquine (CQ) resistance. P. vivax is the other species well established to be capable of evasion from antimalarial drug action. P. vivax drug resistance has been initially described against anti-fo…
Despite the major recent progress towards malaria elimination in Latin America and the Caribbean, focal transmission persists mostly across the Amazon Basin and the Pacific and Atlantic Coast of Colombia and Central America, where Plasmodium vivax accounts for nearly 80% if the cases. One distinctive feature of P. vivax associated with its increased resilience is the ability to stay in th…
SARS-CoV-2 has now spread globally and poses a major challenge for low- and middle-income countries, where local health infrastructure can be quickly overwhelmed. This proposal builds upon ongoing, FAPESP-supported field research to address the microepidemiology and control of SARS-CoV-2 infection in Mâncio Lima, an urban community in the Amazon. The overarching goal is translating field-…
(Only some records are available in English at this moment)
The current proposal focuses on the vast but clinically silent human reservoir of P. vivax infection that remains undetected and untreated across the Amazon Basin. We will systematically explore the large volume of individual-level data generated by population-based surveys led by the collaborating investigators in endemic settings in Brazil and Peru, combined with aggregated data generat…
During his 2-week visit to Brazil, it is expected that Prof. Duraisingh will provide training in the following activities: 1. Reticulocyte enrichment from erythrocyte preparations, using gradient centrifugation techniques; 2. Optimization of freezing/thawing conditions for field-collected P. vivax samples; 3. Optimization of ex-vivo assays for schizont maturation and subsequent invasion o…
Nearly 130,000 laboratory-confirmed cases of malaria were recorded in Brazil in 2016, 99.5% of them acquired in the Amazon Basin. Plasmodium vivax accounts for 88% of the malaria burden in this country, with P. falciparum being the second most prevalent malaria parasite. New episodes of P. vivax blood-stage infection may be caused by new inoculations with sporozoites (primary infections) …
(Only some records are available in English at this moment)
SARS-CoV-2 has now spread globally and poses a major challenge for low- and middle-income countries, where local health infrastructure can be quickly overwhelmed. This proposal builds upon ongoing, FAPESP-supported field research to address the microepidemiology and control of SARS-CoV-2 infection in Mâncio Lima, an urban community in the Amazon. The overarching goal is translating field-…
P. vivax challenges Malaria control, surpasses P. falciparum distribution and subjects 2,5 billion people to the risk of being infected. Naturally acquired immunity, observed on individuals exposed to several Malaria episodes, does not prevents infection but limits parasitaemia, preventing it´s escalation and the manifestation of symptoms. Clinical immunity to Malaria in P. falciparum end…
Brazil recorded 193 thousand cases of Malaria in 2017, an increase of 51% over the previous year. More than 99% of Malaria cases in the country are acquired in the Amazon Basin. The Alto Juruá Valley, with about 120.000 inhabitants, concentrates more than 40% of all P. falciparum infections diagnosed in Brazil and almost 20% of all cases, independently of the species. One of the possible …
With 143,910 laboratory-confirmed cases and 41 malaria-related deaths in 2014, Brazil has now the lowest malaria burden in 35 years, with transmission virtually limited to the Amazon Basin. Accordingly, the Ministry of Health of Brazil has launched, in November 2015, the Malaria Elimination Plan, with the short-term goal of interrupting Plasmodium falciparum transmission countrywide over …
With 143,910 laboratory-confirmed cases and 41 malaria-related deaths in 2014, Brazil has launched, in November 2015, the Malaria Elimination Plan, with the short-term goal of interrupting Plasmodium falciparum transmission countrywide over the next 15 years. The focal nature of malaria transmission in Brazil suggests that elimination efforts will require a careful prioritization of a few…
Approximately 212 million malaria cases and more than 400,000 deaths are registered annually in the world. In Brazil, 143,000 malaria cases were recorded in 2014, 88% of which were due to Plasmodium vivax. Merozoites are stages of the parasite responsible for the invasion and destruction of red blood cells, causing clinical symptoms of malaria.They are covered by several merozoite surface…
(Only some records are available in English at this moment)
This is a proposal for a 12-month research internship at the Harvard T. H. Chan School of Public Health, under the supervision of Dr. Marcia Caldas de Castro. The main aim is obtaining further training in statistical and geospatial methods for data analysis to test whether the periodic application of an environmentally safe biolarvicide (VectoMax FG, 20 kg/ha) in fish farming ponds can re…
This is a proposal for a twelve-month internship at the Department of Immunology and Infectious Diseases at Harvard T.H. Chan School of Public Health, under the supervision of Prof. Duraisingh, who is an international expert in the area of investigation of the biology of the blood stages of Plasmodium. The central objective of this stage will be to investigate the biological activity of a…
This a proposal for a seven month period internship at the Department of Parasitology in Leiden University Medical Center (LUMC) under the supervision of Dr. Maria Yazdanbakhsh, who exercises leadership and recognized international excellence in immunology of filariasis. The main objective of this short-term research project is analyze field-collected peripheral blood mononuclear cell sam…
(Only some records are available in English at this moment)
| 7 / 7 | Ongoing research grants |
| 25 / 14 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 28 / 12 | Completed scholarships in Brazil |
| 4 / 4 | Completed scholarships abroad |
| 67 / 40 | All research grants and scholarships |
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