bachelor's at Bachaelado Em Ciências Biológicas Mod Médicas from Universidade Federal de São Paulo (1985), master's at Biochemistry from Universidade Federal de São Paulo (1989) and doctorate at Biochemistry from Universidade Federal de São Paulo (1995). Has experience in Biochemistry, acting on the following subjects: heparin, cathepsin b, heparan sulfate, glycosaminoglycans and cysteine proteinase. (Source: Lattes Curriculum)
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Heparam sulfate (HS), a sulfated linear carbohydrate that decorates the cell surface and the extracellular matrix, is widely distributed among the various phyla of the Animal Kingdom and represents a key regulator of biological processes. Its biosynthesis, in the form of proteoglycans (PGs), occurs mainly in the lumen of the Golgi apparatus, after its initiation in the lumen of the endopl…
As a consequence of the surge in demand for biofuels, ethanol-producing microorganisms, such as the bacterium Z. mobilis, are of considerable interest. Importantly, Z. mobilis has an ethanol production rate and yield significantly higher than that of yeast, and tolerates high levels of ethanol, a virtually unique property among bacteria. We found that Z. mobilis is responsive to the quoru…
The glycoconjugates, including glycosaminoglycans (GAGs), belong to the most abundant class of structurally diverse and heterogeneous molecules present in the extracellular matrix and on the cell surface. Unlike nucleic acids and proteins, the information necessary for their biosynthesis does not have a known code. The diverse and heterogeneous structures are the result of the action of g…
The human HTRA1 enzyme (High-Temperature Requirement protein A1, Q92743 Uniprot) is a 51 kDa non-glycosylated serine protease located primarily in the extracellular environment. This enzyme is involved in the remodeling of the extracellular matrix (ECM) by degrading its components, such as decorim, fibronectin, aggrecam and collagen. The mode of action of HTRA1 is related to its serine pr…
| 7 / 3 | Completed research grants |
| 4 / 1 | Completed scholarships in Brazil |
| 11 / 4 | All research grants and scholarships |
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CV Lattes
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