Bruna Gregatti de Carvalho in research grants and scholarships supported by FAPESP.
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This research project aims to develop multifunctional systems to release nanovectors for co-delivery of nucleic acids into cells. In this project, two important aspects will be explored for gene therapy improvement: (i) the development of nanovectors for co-delivery of plasmid DNA (pDNA) and small interfering (siRNA-silencer); and (ii) the synthesis of hybrid micro-carrier system composed…
This research project aims to develop alginate/fibroin and alginate/chondroitin sulphate polymer blends to synthesize hybrid hydrogel microparticles. These hybrid microparticles will be used as micro-carriers in gene therapy for the sustained release of non-viral vectors. Gene therapy requires the transfer of genetic materials by transfection or transduction of cells; and thus needs speci…
Besides various applications of metallic nanoparticles, DNA sensors are devices that combine the selectivity of DNA with the nanoparticles' sensitivity. This technology development is required whereas similar symptoms are caused by different organisms contaminations. This is the case of the fungus Paracoccidoides brasiliensis that can be breath in and installed in the lungs. The symptoms …
Gene therapy is a therapeutic strategy based on the intracellular delivery of genetic material (DNA or RNA). It is particularly promising to treat severe diseases for which the pathophysiology and genetic targets are known, e.g., cancer. In general, the success of gene therapy depends on (I) the protection of genetic material against nuclease-mediated degradation in the body fluids and (I…
| 3 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 4 / 4 | All Scholarships |
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