Vitor Barbanti Pereira Leite in research grants and scholarships supported by FAPESP.
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The approach of energy landscapes has significantly contributed to the understanding of complex molecular systems such as the protein folding problem. In this scenario, minimalist and simplified models have played a key role. This project will focus on biological macromolecules, in which we will study the energy landscape of proteins and RNAs using simplified computational models and stat…
Understanding the relationship between structure, energetics and functional dynamics of proteins is a major challenge in molecular biophysics. In this project, we will bring together a bi-national, multi-institutional team of leading research groups that will aim to reveal how molecular disorder is utilized during biological function. In particular, we will investigate how partial transie…
(Only some records are available in English at this moment)
The elucidation of functional mechanisms in proteins is a challenging issue of enormous relevance and important pathologies are associated with their dysfunctions. The energy landscape approach has contributed significantly to the understanding of biomolecular mechanisms, in which the approach to the problem of protein folding is its most notable success. Our group at IBILCE-UNESP has dev…
Folding and functional mechanisms of proteins are fundamental problems inunderstanding biological machinery. Under physiological conditions, proteins are generallycharacterized by native structural conformations. These structures significantly facilitate the investigation of protein functioning, as their structural information serves as order parameters and reaction coordinates of the stu…
Faced with the challenge of understanding the process of protein folding through computational simulations, minimalist physical models have emerged based on different premises and experimental observations. A model that presents efficiency and low computational cost is the model based on structure, in which its potential is obtained through the native structure of a protein. Due to its di…
Malaria is a devastating infectious disease caused by parasites of the genus Plasmodia. Nearly half of the world's population, lives in areas where malaria is endemic and roughly one million deaths in children are reported every year. During the first decade of this century a dozen or so new drugs entered the clinical development and also new ways of accelerating the discovery of antimala…
One of the most difficult challenges in science is to find clean and cheap energy sources. The second generation bioethanol seems to be viable a solution to substitute fossil fuel usage. The bioethanol production makes use of sugarcane biomass residues not used directly in fermentation process. This process involves the degradation of cellulose by specific enzymatic hydrolysis. The techn…
(Only some records are available in English at this moment)
The energy landscape approach has contributed significantly to the understanding of complex molecular systems such as the protein folding problem. In this scenario, minimalist and simplified models have played a fundamental role. This project will focus on biological macromolecules, in which we study the protein and chromatin energy landscape using simplified computational models and stat…
One of the most difficult challenges in science is to find clean and cheap energy sources. The second generation bioethanol seems to be viable a solution to substitute fossil fuel usage. The bioethanol production makes use of sugarcane biomass residues not used directly in the fermentation process. This process involves the degradation of cellulose by specific enzymatic hydrolysis. The t…
| 14 / 11 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 16 / 8 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 34 / 23 | All research grants and scholarships |
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