Marcelo Nicolas Muscara in research grants and scholarships supported by FAPESP.
| News published in Agência FAPESP Newsletter about the researcher |
| More itemsLess items |
| TITULO |
| Articles published in other media outlets ( ): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
The vasorelaxant effects of the endogenous gasotransmitter hydrogen sulfide (H2S), as well as those of its donor compounds, have been demonstrated in some vascular beds. These findings, added to the antioxidant, anti-inflammatory and stimulatory effects of mitochondrial function, make of H2S and its donors, compounds with interesting therapeutic potential for treatment of vascular disease…
In view of the relevance of cardiovascular diseases in public health, the development of new therapeutic strategies is a high-priority issue. Studies carried out over the last decade show the participation of hydrogen sulphide (H2S) in several physiological systems, including the cardiovascular system. In blood vessels, H2S can act on both smooth muscle cells and endothelial cells resulti…
Over the last decade, the endogenous production of hydrogen sulfide (H2S), a well known environmental pollutant, has been characterized in mammals, as well as its participation in several organic functions, such as vascular reactivity, mitochondrial activity and inflammatory response. Regarding the latter aspect, and despite some divergences that appear in the literature concerning the pr…
Inflammation is an adaptive response triggered by noxious stimuli such as infections and tissue damage that aims to restore homeostasis. Chronic destruction of periodontal attachment apparatus due to an intense inflammatory response to bacteria leads to a clinical condition known as periodontal disease. Periodontal inflammation usually causes superficial ulcers in the gingival sulcus, whe…
(Only some records are available in English at this moment)
The scientific literature of the last quarter of a century reports the vascular effects of the endogenous mediator hydrogen sulfide (H2S) and its donor compounds, which, in addition to to the antioxidant, anti-inflammatory and stimulating effects of mitochondrial function, make H2S and its donors compounds with relevant therapeutic potential for the treatment of vascular diseases. In part…
Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease characterized by eczematous lesions associated with severe pruritus and immunoglobulin E (IgE) overproduction that affects children and adults with a high prevalence. Even though some patients respond satisfactorily to topical treatments, this type of therapies are not always effective, and systemic treatments are of…
Hydrogen sulfide (H2S) is a gaseous mediator endogenously produced in mammals mainly by the enzymes cystathionine ³-lyase enzyme (CSE) and cystathionine-²-synthase (CBS) using L-cysteine as substrate. A recent work from our laboratory shows that H2S donors, such as the compound GYY-4137 (slow release) or NaHS (spontaneous release), have anti-nociceptive and antiinflammatory effects on the…
| 1 / 1 | Ongoing research grants |
| 9 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 11 / 2 | Completed scholarships in Brazil |
| 22 / 8 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID