Abstract
Graves' disease (GD) is responsible for 60-80% of patients affected by hyperthyroidism. GD has autoimmune characteristics, with the production of autoantibodies produced by B lymphocytes against thyroid antigens, such as thyroperoxidase, thyroglobulin, TSH receptor, sodium-iodine symporter. Genetic and epigenetic factors have roles in triggering GD, like CTLA4 and TG genes, as well as sub…