Abstract
Rhabdomyolysis syndrome is a disorder known for centuries. However, the causal association between rhabdomyolysis and acute kidney injury (AKI) was first described only during the World War II. The myoglobinuric AKI may be considered the most severe complication of rhabdomyolysis, occurring in 10-50 % of the cases. Using animal models, it has been proposed the following mechanisms to expl…