Abstract
Sickle Cell Anemia (SCA) is an inherited disease caused by the production of abnormal hemoglobin(Hb)S, whose deoxygenation-induced polymerization results in Red Blood Cell (RBC) sickling and numerous pathophysiological consequences. Sickle Cell Disease (SCD) affects approximately 300 000 newborns worldwide each year and is associated with acute and chronic complications, including frequen…