Abstract
The MICA and MICB molecules are constitutively expressed in fibroblasts, monocytes, and epithelial cells. However, their expression may be stimulated in conditions such as cancer, infections, and autoimmune diseases, acting as cellular stress markers. MICA and MICB are encoded on chromosome 6 in the Major Histocompatibility Complex (MHC) region, the most variable region of the human geno…