She studied Biological Sciences at the University of Campinas (1999-2003). PhD in the Laboratory of Endocrine Pancreas and Metabolism, Department of Structural and Functional Biology, Institute of Biology of the same university, being part of this project developed at King's College London (2007-2008), in the Beta Cell Function Study Group. Post-doctoral study in the Laboratory of Endocrine Pancreas and Metabolism (2008-2009). She was a Research Fellow at the Diabetes Study Group, King`s College London, 2009-2012, Fellowship in Diabetes-UK. Served as a Collaborative Researcher (Young Researcher-Fapesp Scholarship and Fellowship) in the Laboratory of Endocrine Pancreas and Metabolism (2013-2014). Currently, she is Adjunct Professor in the IB at University of Campinas, teaches students in the postgraduate course in Functional and Molecular Biology, and co-counselor in the postgraduate Multicentric course. She acts in undergraduate and postgraduate education and in the investigation of the molecular mechanisms involved in insulin secretion, beta cell maintenance and glycemic homeostasis. She has experience in the field of cell signaling, development and pancreatic beta cell function. She is an associate researcher at the Leopoldo de Meis National Network of Education and Science (RNEC). She is an associate researcher at the Obesity and Comorbidities Research Center (OCRC), UNICAMP, and Vicente's mother. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Dysfunctions in pancreatic beta cells can lead to impaired insulin production and secretion, cell death, and type 2 diabetes mellitus (DM2). Understanding the mechanisms that regulate the synthesis of proteins involved in beta cell function and survival is of fundamental importance to understand how such dysfunctions could be avoided. The KH-type splicing regulatory protein (KSRP) modulat…
Type 2 diabetes mellitus (DM2) is an endocrine disorder characterized by the abnormally high concentration of glucose in the blood. The progressive decline of beta cell function by endoplasmic reticulum (ER) stress may occur in response to exposure to excess free fatty acids or inflammatory cytokines during the progression of DM2, activating the UPR (unfolded protein response). In this pr…
Type 2 diabetes mellitus (T2D) is a heterogenic disorder characterised by chronic hyperglycemia, due to the combination of insulin resistance in peripheral tissues and a deficient insulin secretion in pancreatic islets. The cholinergic stimulation is one of the most important mechanisms that regulate the beta-cell function, in which M3 muscaric receptor activation results in an increase i…
Obesity results from an imbalance between energy intake and expenditure. It is often accompanied by insulin resistance, fasting hyperglycemia and several impairments in pancreatic beta cell function and survival, constituting one of the main risk factors for the development of Type 2 Diabetes Mellitus (T2D). Obesity is also associated with the development of hypothalamic inflammation, and…
A diet rich in long-chain saturated fatty acids is capable of causing an inflammatory state in the central nervous system (CNS) by several means, among them elements the activation of the Toll-like receptor 4 (TLR4), resulting in the release of pro-inflammatory cytokines. Hypothalamic nuclei, related to the control of hunger and satiety, are usually compromised and become less responsive …
Obesity is defined as an excessive and abnormal accumulation of fat and is often associated with hypothalamic dysregulation. The consumption of high-fat diets has been considered the main factor responsible for inducing hypothalamic inflammation, commonly found in obese individuals. This inflammation has been associated with chronic hypothalamic resistance to the signs of anorexigenic and…
(Only some records are available in English at this moment)
Nonalcoholic fatty liver disease (NAFLD) is an emerging concern because of its increased prevalence. This disease, caused by high food intake, corresponds to the accumulation of fat in the liver ranging from a simple steatosis to a steatohepatitis. NAFLD has been correlated with disorders such as obesity, insulin resistance and type 2 diabetes mellitus (DM2), which may be associated with …
MicroRNAs (miRs) are short RNA nucleotide sequences that regulate protein synthesis by cleaving messenger RNA (mRNA) or preventing their translation. MiRs are synthesized by a highly specialized process involving protein complexes such as DROSHA and Dicer, RNA polymerases and Argonaut proteins (RISC complex). Some miRs are associated with PDX1, Neurog3 and mafA proteins, transcription fac…
The world health organization stipulates that by 2050 the population will have 2billion elderly people aged 60 and over, approximately 122% more than the current elderly population. With aging, the appearance of chronic diseases such as diabetes, cardiovascular diseases, among other sensory and bodily changes, such as the increase in white adipose tissue and loss of muscle mass, becomes m…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 2 / 2 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 18 / 15 | Completed scholarships in Brazil |
| 25 / 22 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID