Abstract
To adhere to host cells Toxoplasma gondii uses microneme proteins (MICs), making their adhesive domains essential for the parasite virulence. MICs can be found associated with each other on the tachyzoite surface, like the complex TgMIC1/MIC4/MIC6. We have previously demonstrated that pure TgMIC1/MIC4 subcomplex, obtained through adsortion to immobilized lactose, can stimulate macrophages…