Has experience in Biochemistry, focusing on Molecular Biology (Source: Lattes Curriculum)
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The mitochondrial transmembrane protein NAD(P)+ transhydrogenase (NNT) catalyzes the transfer of a hydride between NAD(H) and NADP(H), coupled with the transport of a proton between the intermembrane space and the mitochondrial matrix. This process can occur in the direction of generation of NADPH or NADH (i.e., direct and reverse reactions). The NADPH generated by NNT activity stands out…
The squamous cell carcinoma of head and neck (SCCHN) is a serious global health problem. Cisplatin (CDDP) combined with radiotherapy is given as neoadjuvant, adjuvant, or definitive palliation for patients with the disease. It is well known that both the response to treatment as their side effects vary from individual to individual, which appears to be explained, at least in part, by the …
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CV Lattes
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