Abstract
Prostaglandin E2 (PGE2) is one of the main mediators involved in the differentiation and/or expansion of T helper (Th) Th1 and Th17 cells in inflammatory disorders models, such as experimental autoimmune encephalomyelitis (EAE) and experimental models of colitis. This prostanoid plays an important role in the differentiation of T lymphocyte subpopulations, through PGE2 receptors, EP2 and …