CV Lattes
Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biological Sciences from the Federal University of Espírito Santo. Doctorate of Science, Microbiology, University of São Paulo. Post-doctorate, Federal University of São Paulo, Paulista School of Medicine. Affiliate Professor, Federal University of São Paulo, Paulista School of Medicine. Experience in microbiology, parasitology, molecular biology, biotechnology and bioinformatics. Research themes: tranlational research, microbial ecology, environmental microbiology, medical microbiology, protozoology, parasite-host interaction, antiseptic and antimicrobial agents, microbial toxins, cellular and molecular approaches focused on inflammation and healing processes, cellular targets associated with infection mechanisms and personalized medicine. (Source: Lattes Curriculum)
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Free-living amoebae of the genus Acanthamoeba are eukaryotlc organisms, aerobic and widely dispersed in nature, which can inhabit aquatic and terrestrial environments. Over the past year, these protozoa have assumed importance in human diseases, including fatal infections and debilitating diseases, primarily involving the nervous system and eye. Epidemiological data about the encephalitis…
Infections of the corneal surface by free-living amoebae of Acanthamoeba genus, amoebic keratitis, are characterized by acute pain and disability of the patient's visual acuity. Adhesion of trophozoites to epithelial cells of the cornea following injury and tissue invasion processes are important in the establishment of the infection. The damages to the corneal tissue cells and by amoebae…
Free-living amoebae of Acanthamoeba genus are directly related to the corneal epithelium infections. In general, infection of the corneal surface by the protozoan, called amoebic keratitis, affects young and healthy individuals and the exponential increase in the number of cases of Acanthamoeba keratitis has attracted the world's scientific curiosity and attention of the competent health …
Infections caused by virulent strains of Acanthamoeba spp. are commonly related to the properties of invasion and destruction of the host tissue. Maintaining the structural stability of the corneal epithelium is associated with cell adhesion processes-cell and cell-substrate, each cell type has specific junctional structures in accordance with the position and function of the epithelial l…
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