graduation at Odontologia from Universidade Federal da Paraíba (2007), master's at Odontology from Universidade Estadual Paulista Júlio de Mesquita Filho (2010) and doctorate at Odontology from Universidade Estadual Paulista Júlio de Mesquita Filho (2014). Has experience in Odontology, acting on the following subjects: microbiologia, odontologia preventiva, fitoterapia, dentística and crianças. (Source: Lattes Curriculum)
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Organ-on-a-chip has emerged as a tool to improve the predictive power of preclinical analyses through an accurate in vitro representation of human physiology, in many cases replacing animal experimentation. This application is achieved through the convergence of the fields of microfabrication, microfluidics and tissue engineering. Thus, this project proposes the development of three organ…
Tissue Engineering has emerged as an exciting field in Regenerative Medicine to propose alternative methods to regenerate tissues and organs using innovative biofabrication and cell culture methods. Three-dimensional (3D) printing has opened incredible possibilities to provide precise internal and external shape control of biomaterials. In this project, we propose the translation of addit…
The regeneration of mineralized tissues under degenerative inflammatory stimulus is a challenging situation, since the reparative potential of resident stem cells may be negatively influenced in the presence of high dosage of pro-inflammatory mediators. In this research project, an association of tissue engineering techniques will be evaluated in order to develop macro-porous chitosan sca…
Currently, the development of biomaterials into Regenerative Dentistry has been into the spotlight, being studied in association with tissue engineering concepts. Novel technologies have been developed to aid dentin regeneration, by creating from novel biomaterials a favorable environment for dental pulp cells proliferate and differentiate, leading to pulp-dentin complex regeneration. Thi…
The development of bioactive composition and an architectural pattern capable of favoring the infiltration and interaction of precursor cells, along with angiogenesis, are crucial into tissue engineering field. Thus, this project has a proposal to associate simple and cost-effective technologies to develop chitosan scaffolds containing an bioactive mineral phase (calcium carbonate), and p…
Currently, new treatment options have been investigated to stimulate tissue regeneration within minimally invasive concept, by applying a biomaterial that perfectly shape in defected area and capable of stimulating resident cells from pulp and apical papilla to migrate for material's surface and differentiate to produce a new tissue, what is referred as cell homing therapy. Therefore, the…
(Only some records are available in English at this moment)
The use of alloplastic scaffolds for the modulation of local precursor cells has been increasingly highlighted in tissue engineering techniques, suggesting a promising application in the medical and dental fields. An important aspect in of a scaffold are the characteristics of its porosity, such as its organization, hierarchy and interconnectivity between the pores. Therefore, the aim of …
The development of scaffolds for mineralized tissues regeneration by cell homing is an innovative alternative aimed at the establishment of minimally invasive therapies capable to accelerate tissue repair and regeneration. For that, the development of bioactive composition and an architectural pattern capable of favoring the infiltration and interaction of precursor cells, along with angi…
The development of injectable biomaterials, capable of acting as a framework for tissue neo-deposition, presents itself as an innovative proposal within the current concepts of Regenerative Dentistry. Thus, this project presents a strategy for the development of an injectable system based on gelatin-collagen hydrogel (HGel) associated with chitosan (CH) microspheres (MS) loaded with a dru…
(Only some records are available in English at this moment)
Applying tissue engineering strategies to modulate tertiary dentinogenesis has emerged as a promising approach to improve success rate in local dentin regeneration. Scaffolds with nanofiber architecture are capable of increasing the odontoblastic phenotype expression of dental pulp stem cells (DPSCs) due to the similarity with natural extracellular matrix. Additionally, nanofibrous mats c…
In this study, the odontoblastic differentiation of dental pulp stem cells (DPSCs) and their potential to deposit mineralized matrix after being seeded on nanofibrous scaffolds treated or not with bioactive molecules will be assessed. For this purpose, Poli (L-latic acid) nanofibrous scaffolds (NF-PLLA) and nanofibrous hollow microspheres from star-shaped PLLA (HNF-SSPLLA) will be fabric…
| 2 / 2 | Ongoing research grants |
| 1 / 1 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 18 / 18 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 29 / 29 | All research grants and scholarships |
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CV Lattes
ORCID