CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
PhD in Science by the Microbiology, Immunology and Parasitology Program at the Federal University of São Paulo - DMIP (Note Capes 7). During his doctorate, he worked with the heterologous-boost genetic vaccination model using ASP-2 (amastigote surface protein 2) as an antigen for immunizations against Chagas disease. The main objective of the thesis was to study which chemokine and integrin molecules, the Th1 profile, are important to T lymphocytes migration during immunization and/or infection by T. cruzi. During her direct doctorate, the researcher was awarded a research internship abroad by FAPESP and during a year developed the project in the Department of Medicine at the University of Massachusetts Medical School, Worcester (USA). During the internship abroad, the principal goal was performed the RNAseq analysis of T.cruzi-infected effector CD8+ T lymphocytes. The researcher has experience in Flow Cytometry, FlowSight, Cell Sorting, ELISA, ELISPOT and other immune techniques. Strong performance in Molecular Biology such as: PCR, RT-PCR, RNAseq and Microarray techniques. In Celular Biology has extensively expertise in histological section (frozen tissues), Hematoxylin and Eosin, Immunohistochemistry and Confocal Microscopy. In addition, the research has extensive experience in Cell Culture. (Source: Lattes Curriculum)
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The acute renal injury (AKI) is one of the major public health problems in the world. In South America, the incidence of AKI is 31% and in Brazil 5% of the cases correspond to hospitalization and 30% of hospitalizations in the Intensive Care Unit (ICU). One of the causes of AKI is renal Ischemia and Reperfusion Injury (IRI), which is induced by impairment in the delivery of oxygen, nutrie…
Trypanosoma cruzi is the causative agent of Chagas disease, a neglected disease that is endemic in South and Central America, affecting approximately 10 million. CD8 + T cells play a key role in protective immunity against intracellular pathogens such as T. cruzi. The heterologous prime-boost immunization consists of a booster dose with two different genetic vectors carrying the same gene…
CD8+ T cells play a key role in protective immunity against intracellular pathogens such as Trypanosoma cruzi, the causative agent of Chagas' disease. The presence of these effector cells at the sites where pathogens multiply is only possible due to the recirculation after activationin secondary lymphoid organs. The integrin adhesion molecules and chemokine receptors may play a critical r…
(Only some records are available in English at this moment)
CD8+ T lymphocytes play an important role in the control of infections by intracellular pathogens such as Trypanosoma cruzi, the causative agent of Chagas disease. These lymphocytes control the infection by releasing IFN-g or by direct cytotoxicity against infected target cells. To perform such functions, the lymphocytes migrate into the infected tissues, establish a stable contact with a…
| 4 / 4 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 5 / 5 | All Scholarships |
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