CV Lattes
ResearcherID
ORCID
Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho (1992), master's at General Biology from Universidade Estadual de Campinas (1994) and doctorate at Biochemistry from Universidade Estadual de Campinas (1998). Has experience in Pharmacy, focusing on Pharmacy, acting on the following subjects: cultura de células, matriz extracelular, melanoma, crescimento tumoral and invasion and metastasis. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| Piel de laboratorio |
| Laboratory Skin |
| Recreated skin |
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
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| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
The progress in reconstruction of an in vitro three-dimensional skin model that accurately represents the complex human skin microenvironment depends on the advance of tissue engineering. In this way, the 3D bioprinting technique is an emerging technology that allows the precise, hierarchical and automated deposition of cells and biomaterials for the construction of mimetics with greater …
Melanoma is a highly invasive and metastatic cancer, with high rates of mortality and chemoresistance. The MAPK pathway is constitutively activated, and there are already available powerful target-specific chemotherapeutics, such as BRAF inhibitors (vemurafenib and dabrafenib). However, resistance to BRAF inhibitors is observed after about 7 months of treatment, primarily because of the h…
Human melanoma presents extreme chemoresistance and poor prognosis with a high risk of metastasis. The overexpression of MAPK/ERK pathway proteins is closely related to uncontrolled melanoma cells survival, and this route has been studied for the development of targeted therapies. Thus, the recent chemotherapeutics Vemurafenib (BRAF V600E inhibitor) and Trametinib (MEK inhibitor) have bee…
(Only some records are available in English at this moment)
Melanoma is a malignant neoplasm that originates from melanocytes and although it corresponds to only 3% of skin cancers, it is responsible for 80% of deaths. This is because metastatic Melanoma is refractory to conventional and targeted therapies and because it quickly acquires resistance to specific inhibitors of mutated proteins in the MAPK pathway, such as BRAF. In silico screening st…
Melanoma is a complex disease with great aggressiveness and high mortality rates linked to metastatic capacity, immune system evasion and chemoresistance. The microenvironment and transcriptional plasticity, as well as the use of agents for targeted-directed therapy, contribute to the heterogeneity and selection of intrinsically resistant cells or a drug resistance phenotype. Heterogeneit…
Melanoma is a cancer with high mortality rates and high metastatic capacity, resulting from mutations in several genes that confer phenotypic changes, with emphasis on changes in the MAPK signaling pathway especially the mutation in the BRAF protein (V600E). In addition to the use of DNA alkylating drugs, target therapy is already used in the clinics, in which is represented by drugs that…
(Only some records are available in English at this moment)
Melanoma is the less common type of skin cancer, but it is the most aggressive. The most of patients harbor mutations in BRAF (V600E) protein, and its specific inhibitor vemurafenib has revolutionized the treatment of the disease. However, resistance to long-term therapy is recurrent, leading to treatment failure. Besides the acquired resistance, the many different mutations responsible f…
Melanoma is a malignant neoplasm that originates from melanocytes and represents a major public health problem. Although it accounts for only 3% of skin cancers, it is responsible for 80% of malignant neoplasms related to this organ. This is due to the fact that metastatic melanoma is refractory to conventional and targeted therapies and rapidly acquiring resistance to the specific inhibi…
(Only some records are available in English at this moment)
In cancer, intra-tumour phenotypic heterogeneity imposed by a dynamic microenvironment is increasingly recognized as a source of drug-resistance and a driver of metastatic spread. The in vivo microenvironment is highly complex and cancer cells will be exposed to a wide range of stresses including oxygen and nutrient limitation. The ability of cells to respond to the stresses encountered i…
Melanoma represents the deadliest of all skin cancers. The comparison of melanoma incidence and mortality rates indicated a worse prognosis with increasing age. Patients with melanoma demonstrated an inverse correlation of melanoma mortality and incidence of sentinel node metastasis in young and old patients. The Wnt5A and HAPLN1 proteins are altered in the aged microenvironment, they see…
Nowadays billions of people use hair dyes, among them, the most representative class are the permanent hair dyes reaching up to 80% of worldwide consumption. Permanent hair dyes are formed after successive reactions between a primary intermediate (ex. p-phenylenediamine) and a coupler (ex. Resorcinol) that after oxidative reactions with hydrogen peroxide (H2O2) results in permanent color …
(Only some records are available in English at this moment)
| 3 / 3 | Ongoing research grants |
| 13 / 11 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 31 / 22 | Completed scholarships in Brazil |
| 9 / 7 | Completed scholarships abroad |
| 60 / 47 | All research grants and scholarships |
| Associated processes | |
FAIAO-FLORES, FERNANDA; EMMONS, MICHAEL F.; DURANTE, MICHAEL A.; KINOSE, FUMI; SAHA, BISWARUP; FANG, BIN; KOOMEN, JOHN M.; CHELLAPPAN, SRIKUMAR P.; MARIA-ENGLER, SILVYA STUCHI; RIX, UWE; et al. HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma. Clinical Cancer Research, v. 25, n. 18, p. 5686-5701, SEP 2019. Web of Science Citations: 5. (13/05172-4, 15/10821-7)
ALVES-FERNANDES, DEBORA KRISTINA; DE OLIVEIR, ERICA APARECIDA; FAIAO-FLORES, FERNANDA; ALICEA-REBECCA, GRETCHEN; WEERARATNA, ASHANI T.; SMALLEY, KEIRAN S. M.; DE MORAES BARROS, SILVIA BERLANGA; MARIA-ENGLER, SILVYA STUCHI. ER stress promotes antitumor effects in BRAFi/MEKi resistant human melanoma induced by natural compound 4-nerolidylcathecol (4-NC). PHARMACOLOGICAL RESEARCH, v. 141, p. 63-72, MAR 2019. Web of Science Citations: 1. (17/07010-2, 14/24400-0, 14/06959-0, 17/04926-6)
PEDROSA, TATIANA DO NASCIMENTO; CATARINO, CAROLINA MOTTER; PENNACCHI, PAULA COMUNE; DE ASSIS, SILVIA ROMANO; GIMENES, FABRICIA; LOPES CONSOLARO, MARCIA EDILAINE; DE MORAES BARROS, SILVIA BERLANGA; MARIA-ENGLER, SILVYA STUCHI. A new reconstructed human epidermis for in vitro skin irritation testing. TOXICOLOGY IN VITRO, v. 42, p. 31-37, AUG 2017. Web of Science Citations: 6. (14/24400-0, 11/07441-7, 13/12682-9, 11/14327-6, 11/22812-1, 13/00735-0)
CARVALHO, VANESSA F. M.; MIGOTTO, AMANDA; GIACONE, DANIELA V.; DE LEMOS, DEBORA P.; ZANONI, THALITA B.; MARIA-ENGLER, SILVYA S.; COSTA-LOTUFO, LETICIA V.; LOPES, LUCIANA B.. Co-encapsulation of paclitaxel and C6 ceramide in tributyrin-containing nanocarriers improve co-localization in the skin and potentiate cytotoxic effects in 2D and 3D models. European Journal of Pharmaceutical Sciences, v. 109, p. 131-143, NOV 15 2017. Web of Science Citations: 9. (16/04913-9, 13/16617-7, 14/24400-0, 15/23976-9)
FAIAO-FLORES, FERNANDA; QUINCOCES SUAREZ, JOSE AGUSTIN; FRUET, ANDREA COSTA; MARIA-ENGLER, SILVYA STUCHI; PARDI, PAULO CELSO; MARIA, DURVANEI AUGUSTO. Curcumin Analog DM-1 in Monotherapy or Combinatory Treatment with Dacarbazine as a Strategy to Inhibit In Vivo Melanoma Progression. PLoS One, v. 10, n. 3, MAR 5 2015. Web of Science Citations: 13. (11/50435-8)
SANDRI, SILVANA; WATANABE, LUIS R. M.; DE OLIVEIRA, ERICA APARECIDA; FAIAO-FLORES, FERNANDA; MIGLIORINI, SILENE; TIAGO, MANOELA; FELIPE-SILVA, ALOISIO; VAZQUEZ, VINICIUS DE LIMA; SOUZA, PAOLA DA COSTA; LOPES CONSOLARO, MARCIA EDILAINE; et al. Indoleamine 2,3-dioxygenase in melanoma progression and BRAF inhibitor resistance. PHARMACOLOGICAL RESEARCH, v. 159, SEP 2020. Web of Science Citations: 0. (17/04926-6, 17/26148-5, 12/05910-2, 11/19045-9, 16/16554-3, 13/05172-4, 15/10821-7)
ALVES-FERNANDES, DEBORA KRISTINA; DE OLIVEIRA, ERICA APARECIDA; HASTREITER, ARACELI APARECIDA; FAIAO-FLORES, FERNANDA; FELIPE-SILVA, ALOISIO SOUZA; TURATO, WALTER; FOCK, RICARDO AMBROSIO; MARIA-ENGLER, SILVYA STUCHI; DE MORAES BARROS, SILVIA BERLANGA. In vivo antitumoral effect of 4-nerolidylcatechol (4-NC) in NRAS-mutant human melanoma. Food and Chemical Toxicology, v. 141, JUL 2020. Web of Science Citations: 0. (17/07010-2, 14/24400-0, 14/06959-0, 17/04926-6)
DISCACCIATI, MICHELLE G.; GIMENES, FABRCIA; PENNACCHI, PAULA C.; FAIAO-FLORES, FERNANDA; ZEFERINO, LUIZ C.; DERCHAIN, SOPHIE M.; TEIXEIRA, JULIO C.; COSTA, MARIA C.; ZONTA, MARCO; TERMINI, LARA; et al. MMP-9/RECK Imbalance: A Mechanism Associated with High-Grade Cervical Lesions and Genital Infection by Human Papillomavirus and Chlamydia trachomatis. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, v. 24, n. 10, p. 1539-1547, OCT 2015. Web of Science Citations: 10. (12/09746-2, 08/03232-1)
ZANONI, THALITA B.; HUDARI, FELIPE; MUNNIA, ARMELLE; PELUSO, MARCO; GODSCHALK, ROGER W.; ZANONI, MARIA VALNICE B.; DEN HARTOG, GERTJAN J. M.; BAST, AALT; BARROS, SILVIA B. M.; MARIA-ENGLER, SILVYA S.; et al. The oxidation of p-phenylenediamine, an ingredient used for permanent hair dyeing purposes, leads to the formation of hydroxyl radicals: Oxidative stress and DNA damage in human immortalized keratinocytes. Toxicology Letters, v. 239, n. 3, p. 194-204, DEC 15 2015. Web of Science Citations: 11. (08/10449-7, 12/05961-6, 10/07116-6)
FAIAO-FLORES, FERNANDA; QUINCOCES SUAREZ, JOSE AGUSTIN; MARIA-ENGLER, SILVYA STUCHI; SOTO-CERRATO, VANESSA; PEREZ-TOMAS, RICARDO; MARIA, DURVANEI AUGUSTO. The curcumin analog DM-1 induces apoptotic cell death in melanoma. TUMOR BIOLOGY, v. 34, n. 2, p. 1119-1129, APR 2013. Web of Science Citations: 15. (11/50435-8, 08/58817-4)
FAIAO-FLORES, FERNANDA; PINTO COELHO, PAULO ROGERIO; TOLEDO ARRUDA-NETO, JOAO DIAS; MARIA-ENGLER, SILVYA STUCHI; TIAGO, MANOELA; CAPELOZZI, VERA LUIZA; GIORGI, RICARDO RODRIGUES; MARIA, DURVANEI AUGUSTO. Apoptosis through Bcl-2/Bax and Cleaved Caspase Up-Regulation in Melanoma Treated by Boron Neutron Capture Therapy. PLoS One, v. 8, n. 3, MAR 20 2013. Web of Science Citations: 12. (08/58817-4)
SILVEIRA CORREA, TATIANA C.; MASSARO, RENATO RAMOS; BROHEM, CARLA ABDO; TABOGA, SEBASTIAO ROBERTO; LAMERS, MARCELO LAZZARON; SANTOS, MARINILCE FAGUNDES; MARIA-ENGLER, SILVYA STUCHI. RECK-Mediated Inhibition of Glioma Migration and Invasion. Journal of Cellular Biochemistry, v. 110, n. 1, p. 52-61, MAY 1 2010. Web of Science Citations: 32.
MATHEUS, ERIKA R.; ZONTA, MARCO A.; DISCACCIATI, MICHELLE G.; PARUCI, PRISCILA; VELAME, FERNANDA; CARDEAL, LAURA B. S.; BARROS, SILVIA B. M.; PIGNATARI, ANTONIO C.; MARIA-ENGLER, SILVYA S.. MMP-9 Expression Increases According to the Grade of Squamous Intraepithelial Lesion in Cervical Smears. DIAGNOSTIC CYTOPATHOLOGY, v. 42, n. 10, p. 827-833, OCT 2014. Web of Science Citations: 5. (08/58817-4, 12/09746-2)
REBECCA, VITO W.; MASSARO, RENATO R.; FEDORENKO, INNA V.; SONDAK, VERNON K.; ANDERSON, ALEXANDER R. A.; KIM, EUNJUNG; AMARAVADI, RAVI K.; MARIA-ENGLER, SILVYA S.; MESSINA, JANE L.; GIBNEY, GEOFFREY T.; et al. Inhibition of autophagy enhances the effects of the AKT inhibitor MK-2206 when combined with paclitaxel and carboplatin in BRAF wild-type melanoma. PIGMENT CELL & MELANOMA RESEARCH, v. 27, n. 3, p. 465-478, MAY 2014. Web of Science Citations: 27. (12/05732-7)
HIEDA, DANIELE SEO; DA COSTA CARVALHO, LARISSA ANASTACIO; DE MELLO, BARBARA VAZ; DE OLIVEIRA, ERICA APARECIDA; DE ASSIS, SILVIA ROMANO; WU, JOANNA; DU-THUMM, LAURENCE; VIANA DA SILVA, CLAUDIA LARISSA; ROUBICEK, DEBORAH ARNSDORFF; MARIA-ENGLER, SILVYA STUCHI; et al. Air Particulate Matter Induces Skin Barrier Dysfunction and Water Transport Alteration on a Reconstructed Human Epidermis Model. JOURNAL OF INVESTIGATIVE DERMATOLOGY, v. 140, n. 12, p. 2343+, DEC 2020. (18/14936-1, 16/19963-1, 17/04926-6)
MASSARO, R. R.; FAIAO-FLORES, F.; REBECCA, V. W.; SANDRI, S.; ALVES-FERNANDES, D. K.; PENNACCHI, P. C.; SMALLEY, K. S. M.; MARIA-ENGLER, S. S.. Inhibition of proliferation and invasion in 2D and 3D models by 2-methoxyestradiol in human melanoma cells. PHARMACOLOGICAL RESEARCH, v. 119, p. 242-250, MAR 2017. (12/05732-7, 15/10821-7, 14/24400-0, 13/05172-4)
DE OLIVEIRA, ERICA APARECIDA; DE LIMA, DIOGENES SAULO; CARDOZO, LUCAS ESTEVES; DE SOUZA, GARCIA FERREIRA; DE SOUZA, NAYANE; ALVES-FERNANDES, DEBORA KRISTINA; FAIAO-FLORES, FERNANDA; PABLO QUINCOCES, JOSE AGUSTIN; DE MORAES BARROS, SILVIA BERLANGA; NAKAYA, HELDER I.; et al. Toxicogenomic and bioinformatics platforms to identify key molecular mechanisms of a curcumin-analogue DM-1 toxicity in melanoma cells. PHARMACOLOGICAL RESEARCH, v. 125, n. B, p. 178-187, NOV 2017. (14/24400-0)
SANDRI, SILVANA; FAIAO-FLORES, FERNANDA; TIAGO, MANOELA; PENNACCHI, PAULA COMUNE; MASSARO, RENATO RAMOS; ALVES-FERNANDES, DEBORA KRISTINA; BERARDINELLI, GUSTAVO NORIZ; EVANGELISTA, ADRIANE FEIJO; VAZQUEZ, VINICIUS DE LIMA; REIS, RUI MANUEL; et al. Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation. PHARMACOLOGICAL RESEARCH, v. 111, p. 523-533, SEP 2016. (14/24400-0, 13/05172-4)
PEDROSA, TATIANA DO NASCIMENTO; DE VUYST, EVELYNE; MOUND, ABDALLAH; DE ROUVROIT, CATHERINE LAMBERT; MARIA-ENGLER, SILVYA STUCHI; POUMAY, YVES. Methyl-beta-cyclodextrin treatment combined to incubation with interleukin-4 reproduces major features of atopic dermatitis in a 3D-culture model. ARCHIVES OF DERMATOLOGICAL RESEARCH, v. 309, n. 1, p. 63-69, JAN 2017. (15/23938-0)
TIAGO, MANOELA; DE OLIVEIRA, EDSON MENDES; BROHEM, CARLA ABDO; PENNACCHI, PAULA COMUNE; PAES, RAFAEL DUARTE; HAGA, RAQUEL BRANDAO; CAMPA, ANA; DE MORAES BARROS, SILVIA BERLANGA; SMALLEY, KEIRAN S.; MARIA-ENGLER, SILVYA STUCHI. Fibroblasts Protect Melanoma Cells from the Cytotoxic Effects of Doxorubicin. TISSUE ENGINEERING PART A, v. 20, n. 17-18, p. 2412-2421, SEP 2014. (11/19045-9, 10/15919-1)
BROHEM, CARLA A.; MASSARO, RENATO R.; TIAGO, MANOELA; MARINHO, CAMILA E.; JASIULIONIS, MIRIAM G.; DE ALMEIDA, REBECA L.; RIVELLI, DIOGO P.; ALBUQUERQUE, RENATA C.; DE OLIVEIRA, TIAGO F.; DE MELO LOUREIRO, ANA P.; et al. Proteasome inhibition and ROS generation by 4-nerolidylcatechol induces melanoma cell death. PIGMENT CELL & MELANOMA RESEARCH, v. 25, n. 3, p. 354-369, MAY 2012. (06/50479-7, 09/54816-6, 08/58817-4)
MALLAUPOMA CAMARENA, DENISSE ESTHER; ALCANTARA SEKIMOTO MATSUYAMA, LARISSA SATIKO; MARIA-ENGLER, SILVYA STUCHI; CATALANI, LUIZ HENRIQUE. Development of Epidermal Equivalent from Electrospun Synthetic Polymers for In Vitro Irritation/Corrosion Testing. NANOMATERIALS, v. 10, n. 12, DEC 2020. (11/21442-6, 18/13492-2, 17/04926-6, 19/14527-7)
GIACONE, V, DANIELA; DARTORA, VANESSA F. M. C.; DE MATOS, JENYFFER K. R.; PASSOS, JULIA S.; MIRANDA, DANIEL A. G.; DE OLIVEIRA, ERICA A.; SILVEIRA, EDILBERTO R.; COSTA-LOTUFO, V, LETICIA; MARIA-ENGLER, SILVYA S.; LOPES, LUCIANA B.. Effect of nanoemulsion modification with chitosan and sodium alginate on the topical delivery and efficacy of the cytotoxic agent piplartine in 2D and 3D skin cancer models. International Journal of Biological Macromolecules, v. 165, n. A, p. 1055-1065, DEC 15 2020. (17/04174-4, 17/07856-9, 20/01208-8, 18/13877-1, 16/16554-3, 15/17177-6, 18/18813-1)
LIMA, FLAVIA A.; VILELA, RAQUEL V. R.; OREFICE, RODRIGO L.; SILVA, IZABELA R.; REIS, EDUARDO C. O.; CARVALHO, LARISSA A. C.; MARIA-ENGLER, SILVYA S.; FERREIRA, LUCAS A. M.; GOULART, GISELE A. C.. Nanostructured lipid carriers enhances the safety profile of tretinoin: in vitro and healthy human volunteers' studies. Nanomedicine, v. 16, n. 16, JUN 2021. (17/04926-6, 18/14936-1)
ROCHA-BRITO, KARIN J. P.; CLERICI, STEFANO PIATTO; CORDEIRO, HELON GUIMARAES; SCOTA FERREIRA, AMANDA PETRINA; BARRETO FONSECA, EMANUELLA MARIA; GONCALVES, PAOLA R.; ABRANTES, JULIA LAURA F.; MILANI, RENATO; MASSARO, RENATO RAMOS; MARIA-ENGLER, SILVYA STUCHI; et al. Quercetin increases mitochondrial proteins (VDAC and SDH) and downmodulates AXL and PIM-1 tyrosine kinase receptors in NRAS melanoma cells. Biological Chemistry, DEC 2021. (17/04926-6, 18/03593-6, 15/20412-7)
PEDROSA, TATIANA DO NASCIMENTO; CATARINO, CAROLINA MOTTER; PENNACCHI, PAULA COMUNE; DE ASSIS, SILVIA ROMANO; GIMENES, FABRICIA; LOPES CONSOLARO, MARCIA EDILAINE; DE MORAES BARROS, SILVIA BERLANGA; MARIA-ENGLER, SILVYA STUCHI. A new reconstructed human epidermis for in vitro skin irritation testing. TOXICOLOGY IN VITRO, v. 42, p. 31-37, AUG 2017. (13/00735-0, 11/07441-7, 11/14327-6, 14/24400-0, 11/22812-1, 13/12682-9)
ALVES-FERNANDES, DEBORA KRISTINA; DE OLIVEIR, ERICA APARECIDA; FAIAO-FLORES, FERNANDA; ALICEA-REBECCA, GRETCHEN; WEERARATNA, ASHANI T.; SMALLEY, KEIRAN S. M.; DE MORAES BARROS, SILVIA BERLANGA; MARIA-ENGLER, SILVYA STUCHI. ER stress promotes antitumor effects in BRAFi/MEKi resistant human melanoma induced by natural compound 4-nerolidylcathecol (4-NC). PHARMACOLOGICAL RESEARCH, v. 141, p. 63-72, MAR 2019. (14/06959-0, 14/24400-0, 17/04926-6, 17/07010-2)
SANDRI, SILVANA; WATANABE, LUIS R. M.; DE OLIVEIRA, ERICA APARECIDA; FAIAO-FLORES, FERNANDA; MIGLIORINI, SILENE; TIAGO, MANOELA; FELIPE-SILVA, ALOISIO; VAZQUEZ, VINICIUS DE LIMA; SOUZA, PAOLA DA COSTA; LOPES CONSOLARO, MARCIA EDILAINE; et al. Indoleamine 2,3-dioxygenase in melanoma progression and BRAF inhibitor resistance. PHARMACOLOGICAL RESEARCH, v. 159, SEP 2020. (17/04926-6, 17/26148-5, 12/05910-2, 11/19045-9, 16/16554-3, 13/05172-4, 15/10821-7)
FAIAO-FLORES, FERNANDA; EMMONS, MICHAEL F.; DURANTE, MICHAEL A.; KINOSE, FUMI; SAHA, BISWARUP; FANG, BIN; KOOMEN, JOHN M.; CHELLAPPAN, SRIKUMAR P.; MARIA-ENGLER, SILVYA STUCHI; RIX, UWE; et al. HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma. Clinical Cancer Research, v. 25, n. 18, p. 5686-5701, SEP 2019. (15/10821-7, 13/05172-4)
CARVALHO, VANESSA F. M.; MIGOTTO, AMANDA; GIACONE, DANIELA V.; DE LEMOS, DEBORA P.; ZANONI, THALITA B.; MARIA-ENGLER, SILVYA S.; COSTA-LOTUFO, LETICIA V.; LOPES, LUCIANA B.. Co-encapsulation of paclitaxel and C6 ceramide in tributyrin-containing nanocarriers improve co-localization in the skin and potentiate cytotoxic effects in 2D and 3D models. European Journal of Pharmaceutical Sciences, v. 109, p. 131-143, NOV 15 2017. (16/04913-9, 13/16617-7, 14/24400-0, 15/23976-9)
DA SILVA CARDEAL, LAURA BEATRIZ; BOCCARDO, ENRIQUE; TERMINI, LARA; RABACHINI, TATIANA; ANDREOLI, MARIA ANTONIETA; DI LORETO, CELSO; LONGATTO FILHO, ADHEMAR; VILLA, LUISA LINA; MARIA-ENGLER, SILVYA STUCHI. HPV16 Oncoproteins Induce MMPs/RECK-TIMP-2 Imbalance in Primary Keratinocytes: Possible Implications in Cervical Carcinogenesis. PLoS One, v. 7, n. 3, MAR 16 2012. (08/03232-1, 08/58817-4)
FAIAO-FLORES, F.; ALVES-FERNANDES, D. K.; PENNACCHI, P. C.; SANDRI, S.; VICENTE, A. L. S. A.; SCAPULATEMPO-NETO, C.; VAZQUEZ, V. L.; REIS, R. M.; CHAUHAN, J.; GODING, C. R.; et al. Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells. Oncogene, v. 36, n. 13, p. 1849-1861, MAR 30 2017. (15/10821-7, 14/24400-0, 12/04194-1, 13/05172-4)
CATARINO, CAROLINA MOTTER; PEDROSA, TATIANA DO NASCIMENTO; PENNACCHI, PAULA COMUNE; DE ASSIS, SILVIA ROMANO; GIMENES, FABRICIA; LOPES CONSOLARO, MARCIA EDILAINE; DE MORAES BARROS, SILVIA BERLANGA; MARIA-ENGLER, SILVYA STUCHI. Skin corrosion test: a comparison between reconstructed human epidermis and full thickness skin models. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, v. 125, p. 51-57, APR 2018. (13/00735-0, 11/07441-7, 11/14327-6, 11/22812-1, 13/12682-9)
MORENO, ANA C. R.; CLARA, RENAN O.; COIMBRA, JANINE B.; JULIO, ARIANE R.; ALBUQUERQUE, RENATA C.; OLIVEIRA, EDSON M.; MARIA-ENGLER, SILVYA S.; CAMPA, ANA. The expanding roles of 1-methyl-tryptophan (1-MT): in addition to inhibiting kynurenine production, 1-MT activates the synthesis of melatonin in skin cells. FEBS Journal, v. 280, n. 19, p. 4782-4792, OCT 2013. (09/14632-3, 10/15919-1, 09/53800-9)
BROHEM, CARLA A.; MASSARO, RENATO R.; TIAGO, MANOELA; MARINHO, CAMILA E.; JASIULIONIS, MIRIAM G.; DE ALMEIDA, REBECA L.; RIVELLI, DIOGO P.; ALBUQUERQUE, RENATA C.; DE OLIVEIRA, TIAGO F.; DE MELO LOUREIRO, ANA P.; et al. Proteasome inhibition and ROS generation by 4-nerolidylcatechol induces melanoma cell death. PIGMENT CELL & MELANOMA RESEARCH, v. 25, n. 3, p. 354-369, MAY 2012. (06/50479-7, 09/54816-6, 08/58817-4)
MALLAUPOMA CAMARENA, DENISSE ESTHER; ALCANTARA SEKIMOTO MATSUYAMA, LARISSA SATIKO; MARIA-ENGLER, SILVYA STUCHI; CATALANI, LUIZ HENRIQUE. Development of Epidermal Equivalent from Electrospun Synthetic Polymers for In Vitro Irritation/Corrosion Testing. NANOMATERIALS, v. 10, n. 12, DEC 2020. (11/21442-6, 18/13492-2, 17/04926-6, 19/14527-7)
GIACONE, V, DANIELA; DARTORA, VANESSA F. M. C.; DE MATOS, JENYFFER K. R.; PASSOS, JULIA S.; MIRANDA, DANIEL A. G.; DE OLIVEIRA, ERICA A.; SILVEIRA, EDILBERTO R.; COSTA-LOTUFO, V, LETICIA; MARIA-ENGLER, SILVYA S.; LOPES, LUCIANA B.. Effect of nanoemulsion modification with chitosan and sodium alginate on the topical delivery and efficacy of the cytotoxic agent piplartine in 2D and 3D skin cancer models. International Journal of Biological Macromolecules, v. 165, n. A, p. 1055-1065, DEC 15 2020. (17/04174-4, 17/07856-9, 20/01208-8, 18/13877-1, 16/16554-3, 15/17177-6, 18/18813-1)
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