bachelor's at Ciências Biológicas - Modalidade Bacharelado from Universidade Estadual Paulista Júlio de Mesquita Filho (2003), master's at General Biology from Universidade Estadual de Campinas (2006) and doctorate at Morphology from Universidade Federal de Minas Gerais (2011). Has experience in Morphology, focusing on Cytology and Celular Biology, acting on the following subjects: epitélio germinativo, teleostei, morfometria testicular, célula de sertoli and capacidade suporte. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
The applicant is a young outstanding scientist who has published 45 articles (1569 citations, H-index = 15), supervised 5 PhD thesis, coordinated successful project grants (over 500,000 EURO), and became quite early an Associate Professor. His studies were pioneer in developing spermatogonial stem cell (SSC) transplantation in zebrafish, and showing the role of crucial growth factors, Igf…
The environmental pollution is one of the greatest dilemmas of the humanity, specially in urban areas. An improper basic sanitation and water treatment lead to daily discharge of effluents from industry and residences into the water resources. Those effluents contain toxic compounds as the polycyclic aromatic hydrocarbons (PAH) and metals. The PAHs are mainly derived from the combustion o…
Testicular organoids are three dimensional clusters derived from testicular cells that exhibit in vitro same cytoarchitecture and functionality of a testis in vivo. To achieve this, the organoids are originated from stem cells (spermatogonial stem cells) and somatic cells that recapitulate the testis morphogenesis, and mimic the complex cellular and molecular interactions present in the o…
Spermatogonial Stem Cells (SSCs) are the only stem cells in the body capable to transmit the genetic information from species along generations. This feature is due to the potential of these cells to either self-renew or differentiate to give rise to millions of spermatozoa. Recent studies using SSCs have generated promising methods in the aquaculture, such as the SSC transplantation. Thi…
(Only some records are available in English at this moment)
The overarching goal of this research is to investigate new paracrine factors and indentify long noncoding RNAs (lncRNAs) that regulate SSC activity, and develop biotechnological strategies to delaypuberty in fish. Early sexual maturation of males is still one the major problems limiting the furtherdevelopment of aquaculture in the world. Sexual precocity is an undesirable trait in fish w…
(Only some records are available in English at this moment)
RNA is a macromolecule involved in the processes of cell transcription and translation. In recent years, it has been shown that non-coding RNAs (ncRNAs) can act in several mechanisms of cell regulation, from gene expression to chromosomal rearrangements. Thus, a class of 200-1000 nucleotids ncRNAs, the so-called long non-coding RNAs (lncRNAs) has been drawing the attention of the scientif…
Bisphenol-A (BPA) is an industrial compound whose production started in the mid-1950s, since then it has been widely used on a global scale mainly for the manufacture of plastics. Studies have also proven that BPA is an endocrine disruptor, causing damage to the hypothalamic-pituitary-gonad axis of several vertebrates, such as mice, rats, humans, and zebrafish. Alternative analog bispheno…
The process of sexual determination invertebrates can be classified as mechanisms of genetic sex determination (GSD), or as mechanisms of environmental sex determination (ESD). The fish species Oryzias latipes, also known as medaka, is considered a model organism for studies of sexual determination and differentiation, presenting GSD and heterogametic system XX / XY whose "master" gene is…
(Only some records are available in English at this moment)
The Piaractus mesopotamicus, popular named as Pacu, is a Neotropical freshwater fish with high value commercial and potential to fish farming. In captivity, the males of Pacu shows a pattern of gonadal maturation similar to that seen in nature, with late sexual maturity (2-3 years). Since we have a lack of genetic information and limited knowledge about P. mesopotamicus reproduction, furt…
Organoids are tree-dimensional (3D) cell agglomerates that recapitulate de novo tissue morphogenesis, and consequently tissue cytoarchitecture and biological function of a given organ. Two-dimensional (2D) culture systems, such as organotypic cultures, are not optimal to study the complex cell-cell interaction and signaling as observed in vivo. Therefore, 3D culture system can open opport…
The common snook (Centropomus undecimalis) is a protandrous hermaphrodite fish with high value commercial and potential to finfish farming. One of the bottlenecks in the production of common snook consists in obtaining the captive females. For this reason, a broodstock management in controlling sex ratios by manipulating sex change is necessary. Previous experiment was performed using die…
Thyroid hormones (T4/T3) exert several roles on regulating vertebrate homeostasis acting on several physiological processes such as growth, behavior, stress and on the reproductive system. In mammals, the role of thyroid hormones in reproduction has been well investigated, however the interaction between reproduction and thyroid axes is still unknown. This study aims to evaluate the role …
The role of thyroid hormone on testicular development is well described in mammals, however in fish is poorly explored. Considering that in mammals most of the experimental studies to date are focused on thyroid hormone effects on the developing testes, only limited data are available on adult testis and spermatogenesis. Therefore, the aim of this study is to evaluate the effects of thyro…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 7 / 6 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 24 / 21 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 8 / 8 | Completed scholarships abroad |
| 47 / 43 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID