CV Lattes
Fundação Arnaldo Vieira de Carvalho. Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Licenciatura em Química from Universidade Estadual Paulista Júlio de Mesquita Filho (1997), master's at Genetics from Universidade de São Paulo (2000) and doctorate at Biochemistry from Universidade Federal de São Paulo (2004). Has experience in Biochemistry, focusing on Chemistry of Macromolecules, acting on the following subjects: peptide, resin, solvent, polymer and aggregation. (Source: Lattes Curriculum)
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The best known diseases related to peptide aggregation are Alzheimer's, Type II Diabetes, Prion-related Encephalopathies, Huntington´s and Parkinson's, all referred by the general term amyloidosis which is characterized by the deposition of amyloid fibrils in specific tissues, these aggregates being the causative agents of several types of degeneration. This project aims at studying the m…
Breast cancer has been considered a public health problem because it is the second most common type of tumor in women. According to the World Health Organization (WHO), currently more than 14 million people develop breast cancer each year, and this number is expected to increase to more than 21 million by 2030. In the last decade, radiolabeled peptides are being used both in therapy and i…
Although extremely important, the problem of insolubility of peptides and proteins is still far from being fully understood. A high tendency to unite into insoluble aggregates is a serious limitation to the production and use of many peptides and proteins on a broad spectrum of biological and pharmaceutical applications. In physiological terms, the best known cases of pathologies related …
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