Antonio Claudio Tedesco, Chemical, concluded the doctorate in Organic Photochemistry in the University of São Paulo in 1992. He accomplished his Pos-Doc among 1993 to 1995, in the Harvard Medical School , Boston, USA in the area of Photobiology and Photomedicine and between 2004 and 2005 developed a sabbatical in the University of Paris (Paris-V), Institute National of La Sante et of La Recherche Medicale: Paris, (Lab Inserm U-532 - Laboratoire of Dermatologie) in the area of Tissue Engineer. Has work as a São Paulo University representative at University of Sorbonne Paris Cité, for International Affairs from 2016- 2017 in Paris. Full Professor at São Paulo University developing research in area o Photodynamic Therapy, Photobiology and wound healing process. It had published more than 320 papers in specialized newspapers with more than 540 works in annals of scientific events. He presented more than 50 conferences, symposia and seminars. He possesses 11 chapters of book published. He possesses 17 technological products, of which 6 are registered, 37 items of technical production. He guided the work of, 50 Undergraduates students ,27 master's degree dissertations and 28 doctorate thesis and 24 Pos-doctorates students, in the areas of Photobiology and Photomedicine Biophysics, Chemistry, Drug Delivery and. Now it guides 4 Pos-doctorate, 2 Doctorates Thesis and 5 Master and 3 IC. Now it participates in 05 research projects, and it coordinates of 2 of these. Since 1999 it Coordinate and it acts close to an applied clinical Projects in Photodynamic Therapy at São Paulo Medical Hospital at Ribeirão Preto, Brasília (UNB-HRAN) and UNIFESP-SP. He acts at the area of Chemistry and Drug Delivery, with emphasis in Photochemistry, Photobiology and Photomedicine. In their professional activities it interacted with 650 collaborators in joint authorships of scientific works. In his CV Lattes the most frequent terms in the work area of the scientific production, technological and artistic-cultural are: Cancer, Nanotechnology and Drug Delivery Systems, Photodynamic Therapy, Tissue Engineering, Neurodegenerative Diseases. Email atedesco@usp.br, tedesco@ffclrp.usp.br. http://sites.ffclrp.usp.br/nanotecnologiafomed (Source: Lattes Curriculum)
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The central nervous system (CNS) is composed of astrocytes (50%), oligodendrocytes (40%), microglia (5%) and ependymal cells (5%), which provide structural and functional support to neurons. In particular glial tumors (glioma or glioblastoma) are among the most common neoplasms of the CNS and adult arise from astrocytes, oligodendrocytes and their precursors. Glioblastoma multiforme (GBM)…
The central nervous system (CNS) is composed of astrocytes (50%), oligodendrocytes (40%), microglia (5%) and ependymal cells (5%), which provide structural and functional support to neurons. In particular glial tumors (glioma or glioblastoma) are among the most common neoplasms of the CNS and adult arise from astrocytes, oligodendrocytes and their precursors. Glioblastoma multiforme (GBM)…
The central nervous system (CNS) is composed of astrocytes (50%), oligodendrocytes (40%), microglia (5%) and ependymal cells (5%) which provide structural and functional support to neurons. In particular glial tumors (glioma or, glioblastoma) are among ... (AU)
The Raman spectroscopy, as well as the microscopy, has revealed an excellent analytical tool in the chemical area, pharmaceutics, biological and in the sciences of materiaIs, acting as support in the deve/opment and identification of compositions, as well as in the study of the ultra-structure in biological systems. This coupled equipments that allow a deeper vision ofthe cellular systems…
An enormous variety of new therapies has been emerging in the last years as a consequence of progresses in the field of the sciences and the new technologies applied to biological systems. The common fact to all of this proposed new therapeutics is that in many of them that come as innovation is basically the rediscovered of old drugs as ‘new design’. It understands as a ‘new design’, new…
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In this proposal, we intend to develop Delivery Drug Systems (DDS) targeted to receptors of IL-12/IL-23 pro-inflammatory cytokines by specific monoclonal antibodies, seeking to investigate specific uptake and the effect of the drug prednisone in 2D and 3D cellular matrices of the intestinal epithelium of Crohn's Disease patients. The DDS aims to improve the therapeutic efficacy of medicin…
Glioblastoma multiforme (GBM) are brain tumors considered incurable. Current treatmentwith the chemotherapy drug Temozolomide (TMZ) has a high rate of resistance and difficultyin crossing the blood-brain barrier (BBB). Drug delivery implants in the brain region are newpharmacological alternatives that avoid the need for BBB permeation. In a recent study, thecompound ingenol-3-dodecanoate …
Cartilage injuries rarely heal and often lead to degenerative changes in joints. Some therapies, such as autologous chondrocyte transplantation, have some efficacy in the generation of new tissues, however, the surgical procedure requires two surgeries in the same region, and the obstacles to the delivery of live cells prevent the widespread use. In addition, clinical studies comparing ch…
It is estimated that approximately 1.5 billion people worldwide suffer with some kind of disorder of the Central Nervous System (CNS). Therefore, there is a high demand for effective treatments. Due to an increase in the number of elderly in the world population, if there is an increase or improvement of existing treatments, the number of people with diseases of the CNS will be approximat…
(Only some records are available in English at this moment)
Research on novel compatible biomaterials for three-dimensional (3D) bioprinting exhibiting fast crosslinking properties and multiple advanced functions (like good cell viability, transparency, exhibiting good cell fusion potential) used as scaffolds is essential for advances in customized applications in many research fields, including tissue engineering. Many studies have explored such …
The development of increasingly biomimetic human tissue analogs has been a long-standing goal in two important biomedical applications: drug discovery and regenerative medicine. In seeking to understand the safety and effectiveness of newly developed pharmacological therapies and replacement tissues for severely injured non-regenerating tissues and organs, there remains a tremendous unmet…
Photodynamic therapy (PDT) is a last-line curative treatment modality used for several types of cancer. PDT induces the formation of extracellular vesicles (e.g., exosomes) that regulate resistance and survival mechanisms in tumor cells through paracrine signaling. Consequently, the extracellular vesicles enable tumor cells to survive PDT while making non-treated or sublethally afflicted …
This research project is directly associated with the master's project, entitled "Polymeric nanocarriers and photoactive compounds in diagnosis and treatment of neurodegenerative diseases" under process number FAPESP 2015/09125-6, and will also assist in a complementary way in its conclusion. Over the years, there have been many advances in nanotechnology area for the development of nanod…
| 2 / 2 | Ongoing research grants |
| 12 / 5 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 44 / 15 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 4 / 3 | Completed scholarships abroad |
| 64 / 27 | All research grants and scholarships |
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CV Lattes
ORCID