Abstract
Busulfan, a chemotherapeutic drug, causes damage in proliferative tissues such as the seminiferous epithelium. Regarding vitamin B12 stimulating DNA synthesis, the effect of this vitamin in the recovery of the damaged seminiferous epithelium by busulfan, mainly in the spermatogonial cells, will be evaluated. Sixty-four male rats will be distributed into 8 groups (n=8/group). The animals w…