Scientific Director of the Teaching and Research Institute (IEP); Coordinator of the Molecular Oncology Research Center (CPOM); and Scientific Director of the Molecular Diagnostic Laboratory at the Barretos Cancer Hospital, Barretos, SP. Brazil. Invited Associate Professor at the University of Minho School of Medicine (Braga, Portugal). Extraordinary Professor, Pan African Cancer Research Institute, University of Pretoria, South Africa. Graduation in biology, University of Porto (Portuga) l; doctorate in neuro-oncology, IARC (Lyon, France); postdoctoral fellow in cancer genomics, Free University Medical Center (Amsterdam, Netherlands) and IPATIMUP (Porto, Portugal). (Source: Lattes Curriculum)
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The Molecular Oncology Research center (CPOM) was officially opened in August 2010. The creation of this laboratory sought to meet the most demanding quality criteria, and the design of the project was made based on the most modern research centers, emphasizing the practicality of circulation, the ease of access to technological resources and the supervision of trained professionals.In Au…
SUMMARY ANNUAL PLAN 1 - AUDIOVISUAL CONTENT PRODUCTION STUDIO. The Teaching and Research Institute (IEP) of Hospital de Amor, seeks to improve the work carried out by the Distance Education sector (EaD), which started its activities in 2014, through the coordination of the Cancer Education Center. Since then, the sector has provided online courses and training in Health Education with a f…
(Only some records are available in English at this moment)
Colorectal cancer (CCR) is the third most common type of cancer in the world, and in Brazil, it is the second most incident and despite early screening and new treatment strategies, it remains the second most fatal cancer in the world. The intestinal microbiota has been implicated in the development of colorectal cancer. The work of our group has identified the pathogenic role of Fusobact…
Glioblastoma (GBM) is the most common primary intracranial malignant tumor in adults. GBM is extremely invasive and aggressive, accounting for the majority of the 200,000 Central Nervous System (CNS) tumor-related deaths worldwide each year. GBM in children is relatively rare, with distinct molecular characteristics and response to treatment, when compared to adults. The current standard …
Lung cancer is responsible for 1 in 5 cancer deaths worldwide. The high number of deaths is due to the late diagnosis and the low effectiveness of therapeutic strategies. The pulmonary neoplasia can be divided into non-small cells lung cancer (NSCLC), corresponding to 85% of cases, and small cell cancer. Histologically, it can be divided into adenocarcinoma, squamous cell carcinoma, and s…
Glioblastoma (GBM) is one of the most common neoplasia of the central nervous system, is characterized as a highly aggressive and invasive tumor, is related to high mortality rates and a poor prognosis. Currently, the standard treatment of this disease consists of surgical removal of the tumor, followed by chemotherapy associated with the use of temozolomide (TMZ), a DNA alkylating agent.…
Cancer is responsible for a significant and growing number of patients worldwide, and represents the second leading cause of death in many countries. In the search for new therapies, research with natural products has emerged as an alternative and successful source in the development of potential drugs. The species Euphorbia tirucalli, popularly known as ''aveloz'' is used in folk medicin…
The Epidermal Growth Factor Receptor (EGFR) is an important protein which activation leads to the signaling of intracellular pathways that act directly on cell proliferation, migration and survival. Cetuximab (CTX), is an anti-EGFR monoclonal antibody that has been approved for the treatment of Head and Neck Squamous Cell Carcinoma (HNSCC) patients and metastatic Colorectal Cancer (mCRC).…
(Only some records are available in English at this moment)
O glioblastoma é o tumor maligno mais comum e agressivo do sistema nervoso central (SNC) em adultos. O protocolo padrão é cirurgia, radioterapia e quimioterapia adjuvante/comitante com temozolomida. As células cancerígenas geralmente apresentam mecanismos de resistência a esse quimioterápico, comumente associados às vias de reparo do DNA. Para encontrar uma saída para este problema, inves…
Colorectal cancer (CRC) is the third most common cancer in both males and females and the second and fourth leading cause of cancer-related deaths in both sexes worldwide and in Brazil, respectively. Regarding the treatment of CRC, the current standard of care involves tumor removal through surgery and radiotherapy. Lately, more innovative treatments are proposed, such as targeted therapi…
The gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract whose prognosis of the patients is based on criteria including tumor size, mitotic index and localization. Despite of this classification, GIST progression is often inaccurate. The aim of this study is to elucidate the biological role and therapeutic potential biomarker TERT in…
Gliomas are the most frequent and malignant tumors within the Central System Nervous (CNS) tumors. They are an incurable neoplasia, with a survival average of approximately 13 months, and less than 2% of the patients survive 5 years after the treatment. The low success in the treatment of these tumors is, in part, due to the low understanding of their molecular bases. The present project …
| 1 / 1 | Ongoing research grants |
| 9 / 5 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 14 / 13 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 2 / 2 | Completed scholarships abroad |
| 31 / 26 | All research grants and scholarships |
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CV Lattes
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