Bachelor's at Biomedicine (1988), doctor degree in Biotechnology from São Paulo University (2008) and post-doctoral fellow in Immunology at Duke University (2010). Has experience in Immunology and Applied Imunology, focusing the comprehension of immunology and/or hematopoietic cells interaction with stromal cells. Acting on the following subjects: lymphocytes, dendritic cell, stem cells and mesenchymal stem cells. (Source: Lattes Curriculum)
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Tissue cells, either at rest or activated by some pathological condition, are continuously secreting chemokines as a manner of sending information on their location and physiological state to the immune system. The precise positioning of leucocytes inside an organ is crucial for physiological or pathological responses to take place. Secondary lymphoid organs secrete chemokines to enable t…
Lymph nodes are 400 small organs distributed along the body and play an import role in tolerance and immune response. These small organs are composed by a variety of cells, among these cells are the stromal cells, although scarcely studied they seems to play an important role in immunemodulation and peripheral tolerance. On the other hand, stromal cells derived from bone marrow have a per…
Allogeneic hematopoietic stem cell transplantation has been used for hematological diseases and other pathologies treatment over 40 years. Very often this is the only available treatment that leads patients to healing. The effect known as graft versus leukemia (GVL) or graft versus tumor (GVT) is able to eliminate residual disease in several hematological pathologies. Around 25.000 proced…
A major complication and limitation to the broad application of hematopoietic stem cell transplantation (HSCT) is graft-versushost disease (GvHD), which results from immune-mediated attack of recipient tissue by donor T cells contained in the transplant. GvHD accounts for 15-30% of deaths that occur following allogeneic HSCT (Ferrara et al., 2009). Despite recent advances to reduce the in…
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| 1 / 1 | Completed scholarships in Brazil |
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CV Lattes
ORCID