Paula Intasqui Lopes in research grants and scholarships supported by FAPESP.
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Pollution, considered a growing public health problem, has been linked to reduced male fertility. Polluted air contains several toxic substances, of which we can highlight fine inhalable particulate matter (PM2.5), which promotes the disruption of the blood-testis barrier. Therefore, PM2.5 may reach the testis, and lead to testicular oxidative stress and DNA damage of germ cells. Thus, th…
Semen analysis, routinely utilized during infertility investigation, presents low sensitivity and predictive power, which turns essential the identification of new male infertility diagnostic methods. Taking into consideration that sperm functional abnormalities and semen oxidative stress are considered the main mechanisms associated with infertility, their evaluation can provide addition…
The main mechanisms involved in male infertility are changes in the functional quality of spermatozoa and oxidative stress, which can be evaluated in the laboratory in order to obtain further information on male reproductive potential. However, functional tests have no clinical impact, since they show limited accuracy for clinical purposes. Thus, molecular studies of sperm and seminal pla…
Although semen analysis is essential during infertility investigation, and may provide information about male fertile potential, it is insufficient as a diagnostic method of male infertility. Thus, additional methods for its evaluation are required. In this context, evaluating the sperm proteome of fertile and infertile men, as well as the phosphorylated proteins (regulators of post-testi…
| 2 / 2 | Completed research grants |
| 3 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 6 / 6 | All research grants and scholarships |
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