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THE PROCESS OF PRODUCTION AND PURIFICATION OF RECOMBINANT GP43 (RGP43) ISOFORMS IN THE YEAST PICHIA PASTORIS, USE OF RGP43 AND DIAGNOSTIC KIT
| Document type: | Patente |
| Inventor(s): | Rosana Puccia; Kátia Cândido Carvalho |
| Applicant: | Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) ; Universidade Federal de São Paulo (UNIFESP) |
| Deposit date: | September 2007, 27 |
| INPI register: | |
| IPC: | G01N 33/53 C12N 15/81 C12N 15/31 C12N 15/63 C07K 14/37 |
Abstract
A proccess do produce a recombinant gp43 isoforms (rgp43) in the yeast Pichia pastoris through the regulated expression and in high concentration of recombinant gp43 (rgp43) in culture supernatants of P. pastoris, the use of rgp43 in immunodiagnosis of paracoccidioidomycosis (PCM), a diagnostic kit for the immunodiagnostic of PCM containing one of the rgp43 isoform or a pool of the rgp43 isoforms to be employed in immunodiagnostic of PCM in human or not mammal.
| Grantee: | Kátia Cândido Carvalho |
| Principal Investigator: | Rosana Puccia |
| Institution: | Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |
| Grantee: | Rosana Puccia |
| Principal Investigator: | Rosana Puccia |
| Institution: | Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) |
| Support Opportunities: | Research Grants - Support for Intellectual Property Rights and Licensing (PAPI/Nuplitec) |