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PROCESSO DE OBTENÇÃO DE UMA COMPOSIÇÃO LIOFILIZADA DE NANOPARTÍCULAS A BASE DE QUITOSANA CONTENDO BROMELINA, COMPOSIÇÃO LIOFILIZADA DE NANOPARTÍCULAS A BASE DE QUITOSANA CONTENDO BROMELINA E USO NO TRATAMENTO DE FERIDAS

Document type:Patente
Inventor(s): Janaína Artem Ataíde; Danilo Costa Geraldes; Laura de Oliveira Nascimento; Priscila Gava Mazzola
Applicant: Universidade Estadual de Campinas (UNICAMP)
Deposit date: July 2020, 13
INPI register:
PCT/BR2020/050256
IPC: A61K 47/02 A61K 9/14 A61K 38/48 A61K 47/36 A61K 31/722 A61K 47/26
Abstract

(EN) The present invention relates to a process for obtaining a freeze-dried composition of chitosan nanoparticles containing bromelain. Said composition was seen to be stable in relation to enzyme activity using small molecules, such as sugars or amino acids, as freeze-drying additives. In addition, the present invention discloses the use thereof in preparing a medication for treating wounds.


FAPESP's process: 15/15068-5 - DEVELOPMENT OF POLYMERIC PARTICLES AS CARRIER SYSTEMS FOR BIOACTIVE PRODUCTS
Grantee:Janaína Artem Ataide
Principal Investigator:Priscila Gava Mazzola
Institution: Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Farmacêuticas (FCF)
Support Opportunities: Scholarships in Brazil - Master

FAPESP's process: 16/03444-5 - Development of healing pharmaceutical formulation containing bromelain extracted from industrial wastes
Grantee:Priscila Gava Mazzola
Principal Investigator:Priscila Gava Mazzola
Institution: Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Farmacêuticas (FCF)
Support Opportunities: Regular Research Grants

FAPESP's process: 16/02287-3 - Bromelain encapsulation in chitosan nanoparticles
Grantee:Fernanda Mazon Bissaco
Principal Investigator:Priscila Gava Mazzola
Institution: Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Farmacêuticas (FCF)
Support Opportunities: Scholarships in Brazil - Scientific Initiation

FAPESP's process: 16/02282-1 - Stability and release study of encapsulated bromelain in chitosan nanoparticles
Grantee:Eloah Favero Gérios
Principal Investigator:Priscila Gava Mazzola
Institution: Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Farmacêuticas (FCF)
Support Opportunities: Scholarships in Brazil - Scientific Initiation

FAPESP's process: 17/05275-9 - Bromelain encapsulation: stability, release profile, and cytotoxicity
Grantee:Janaína Artem Ataide
Principal Investigator:Priscila Gava Mazzola
Institution: Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Farmacêuticas (FCF)
Support Opportunities: Scholarships abroad - Research Internship - Master's degree

FAPESP's process: 17/05333-9 - Bromelain encapsulation: characterization and stability
Grantee:Eloah Favero Gérios
Principal Investigator:Priscila Gava Mazzola
Institution: Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Farmacêuticas (FCF)
Support Opportunities: Scholarships abroad - Research Internship - Scientific Initiation