Company research projects supported by PIPE Program

Onkos Diagnósticos Moleculares Ltda (Filial)

City: Ribeirão Preto

Research grants

Ongoing (most recent)

Abstract
Worldwide, there are two major problems in the management of patients with thyroid nodules: 1) High number of unnecessary thyroid surgeries. About 60% of the Brazilian population will identify a thyroid nodule at some point in their lives. Of the cases evaluated by biopsy (FNA - fine needle aspiration), between 20-30% will have an indeterminate result, not being possible, by current techn…
Technological validation of the mir-THYpe® molecular testing platform: a suite of solutions based on microRNA profiling and mutation analysis for thyroid nodules, AP.PIPE
Abstract
Unknowing about the primary site of a metastatic disease, that is, its place of origin, categorizing itself as a cancer of unknown primary site (CUP) makes it difficult to target specific treatments to the patient. CUP is 2% of all cancer diagnoses worldwide and is among the top ten causes of death from cancer. The CUP cases share common characteristics such as rapid dissemination, increa…
Update and optimization of the TOT molecular test (tumor origin test) for metastatic tumors of unknown primary origin through multi-omic approaches, AP.PIPE

Completed (most recent)

Abstract
The mir-THYpe® exam is a molecular classifier for indeterminate cytology thyroid nodules, developed by the startup Onkos in partnership with the Cancer Hospital of Barretos. It uses advanced molecular biology techniques (microRNA profiling and mutation analysis) and Artificial Intelligence, showing itself capable of reducing potentially unnecessary thyroid surgeries by up to 74.6%. It has…
Validation in new clinical indications, optimizations and expansion of access and market insertion of the mir-THYpe® test, a molecular classifier of indeterminate thyroid nodules based on microRNA profiling, AP.PIPE

FAPESP support in numbers * Updated September 30, 2023

Total / Available in English