City: Santana de Parnaíba
See other companies with research projects supported by PIPE ProgramIn countries, such as Brazil, China and the United States, there is a continuous and frightening increase in mortality rates from skin cancer in dogs, making it an increasingly important problem for national and global animal health. The annual expenses per patient under treatment arrive on average US $ 40,000 / year, which do not reflect in important therapeutic benefit for the patients.…
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer accounting for about 85% of all lung cancer cases. Its 5-year survival rate remains at approximately 17%. Almost half of cases have locally advanced or widespread metastasis at diagnosis. In addition, it is therapeutically limited. Despite the successful use of small molecule inhibitors, a major problem reminiscent …
The proposal comprises the synthesis of a novel inhibitor of protein B-RAF V600E to treat melanoma (product) and the evaluation in vitro and in vivo of its pharmacological activity. Melanona represents only 4% of the types of skin cancer, but it is considered a highly aggressive disease due to its invasiveness and ability to develop metastasis. The World Health Organization has estimated …
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