Scholarship 24/14824-0 - Cafeína, Ciclismo - BV FAPESP
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The effect of different acute caffeine doses on 4-km cycling time-trial performance in trained cyclists after habituation to caffeine consumption.

Grant number: 24/14824-0
Support Opportunities:Scholarships in Brazil - Doctorate (Direct)
Start date until: October 01, 2024
End date until: September 30, 2026
Field of knowledge:Health Sciences - Physical Education
Principal Investigator:Bryan Saunders
Grantee:Larissa Registro Registro da Costa
Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated research grant:21/06836-0 - Placebo in sports and exercise: prevalence, conditioning and open-placebo, AP.JP2

Abstract

Caffeine has an ergogenic across a wide range of exercise intensities and durations,however, there appears to be substantial variation between individuals when it comes to theperformance response to its supplementation. The potential influence of habitual caffeineconsumption on caffeine's acute ergogenic effect is a hot topic in sports science. There iscontrasting evidence suggesting habitual use of caffeine might reduce its ergogenic effects ormight not influence it. Additionally, there is a hypothesis that any reduction due to chronicingestion may be outweighed by an acute ingestion of a caffeine dose higher than thathabitually consumed. Therefore, this study intends to investigate if the habitual use of caffeinechanges the improvement in exercise performance with caffeine supplementation, and iftolerance does occur, whether a pre-exercise caffeine dose higher than the habitual daily dosemight overcome this tolerance that has developed. In a double-blind, crossover,counterbalanced, and randomized model, forty trained cyclists with low habitualcaffeine intake (¿75 mg/day) will initially undergo 4-km cycling time trials followingingestion of 3 mg/kg of caffeine (PRECAF3), 6 mg/kg of caffeine (PRECAF6), and a placebo(PREPLA). Participants will thereafter be randomly assigned to receive 3 mg/kg of caffeineor placebo (maltodextrin) daily for at least 14 days. After this supplementation period, theywill undergo another set of 4-km time trials following 3 mg/kg of caffeine (POSTCAF3), 6mg/kg of caffeine (POSTCAF6), and a placebo (POSTPLA). This study will be the first tocontrol the habitual consumption of caffeine, determine the influence of habitual caffeine useon exercise performance, and test whether caffeine supplementation with a higher dose thanthat habitually consumed may overcome any tolerance to its ergogenic effect. The results ofthis study will be of great relevance for athletes that use caffeine habitually and might impactthe trial designs of future studies.

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