Advanced search
Start date

Productive and economic viability of the inclusion of nucleotides in diets based on plant ingredients for tambaqui (Colossoma macropomum)

Grant number: 22/15957-8
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): January 01, 2024
Effective date (End): August 31, 2026
Field of knowledge:Agronomical Sciences - Animal Husbandry - Animal Nutrition and Feeding
Principal Investigator:Leonardo Susumu Takahashi
Grantee:Maria Karolaine Moriman Delgado
Host Institution: Centro de Aquicultura (CAUNESP). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil


Nucleotides (NTs) are functional supplements composed of a nitrogenous base, phosphate group and sugar. They are considered conditionally essential nutrients as they play key roles in the functioning of the animal organism. Dietary supplementation of NTs has been shown to increase the growth and palatability of the diet, promote intestinal development and repair, as well as increase the activities of digestive enzymes and provide immunomodulatory effects in fish challenged with pathogens. However, to date, no studies have been verified that addressed the interactive effect between all-vegetable diets and NTs levels on tambaqui growth, intestinal structure and immunity. In this context, the objective of this proposal will be to evaluate the productive and economic feasibility of supplementing a mixture of nucleotides in diets based on plant ingredients for tambaqui juveniles challenged with the pathogen Aeromos hidrophyla. For this, assays will be conducted for a period of 120 days and analyzes of performance, intestinal histomorphometry, immunological responses and economic viability will be performed. A basal diet will be formulated exclusively with plant ingredients and supplemented with 6 levels of a nucleotide mixture (0.0, 2.0, 4.0, 6.0, 8.0 and 10.0 g kg-1 of diet) . A completely randomized design will be used with 6 treatments with 4 replications each. It is expected that the inclusion of nucleotides in a diet formulated based on plant ingredients provides better growth, intestinal structure and immune responses of tambaqui juveniles submitted to bacterial challenge, in addition to reducing production costs with the feed due to a better use of the diet.

News published in Agência FAPESP Newsletter about the scholarship:
Articles published in other media outlets (0 total):
More itemsLess items

Please report errors in scientific publications list using this form.