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MULTI-OHMIC ANALYSIS OF THE METABOLISM AND MICROBIOME OF HEALTHY DOGS AND CATS AND OF THOSE WITH CHRONIC KIDNEY DISEASE

Grant number: 23/07727-5
Support Opportunities:Scholarships in Brazil - Master
Effective date (Start): August 01, 2023
Effective date (End): July 31, 2025
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
Principal Investigator:Thiago Henrique Annibale Vendramini
Grantee:Laís Oyama Cotrim Lima
Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated research grant:22/06499-6 - Multi-omic analysis of metabolism and microbiota of healthy and sick dogs and cats, AP.GR

Abstract

The application of metabolomic associated to CKD is particularly attractive, for these molecules are associated not only to the reduction of renal excretion and identification of new biomarkers, but with the microbiote and metabolic alterations that constantly occur in the animal organism. With the possibility of identifying these new metabolytes, mechanisms correlated with the physiopathology of CKD may be elucidated. Moreover, evaluating the short-term effects caused by alterations on the 'ohmic' sciences and of microbiote over the influence of precocious therapeutic measures in attempt to reduce the rate of the disease's progression makes us believe in this promising line of study.

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