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"In Vitro" Bioavailability of Main Mycotoxins Found in Food Samples and Exposure Assessment

Grant number: 23/05597-7
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): July 01, 2023
Effective date (End): June 30, 2024
Field of knowledge:Agronomical Sciences - Food Science and Technology
Principal Investigator:Carlos Augusto Fernandes de Oliveira
Grantee:Sibelle Dutra Mendonça
Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil
Associated research grant:19/21603-1 - Biomarker approaches for assessing the early life exposure to multiple mycotoxins in the diet, AP.TEM


Mycotoxins are secondary metabolites produced by fungi that occur naturally in foodstuffs, which can cause a large variety of toxic effects on vertebrates, including humans. The fact that some mycotoxins are carcinogenic (e.g., aflatoxins) and could be detected in breast milk, food and feedstuffs constitutes a serious human and animal health threat, mainly to children and young animals due to their high physiological vulnerability. The objective of this Work Package (WP) is to determine the "in vitro" bioavailability of regulated mycotoxins in Brazil, and adjust the exposure assessment of children to mycotoxins obtained in another WP of the Thematic Project through food data and biomarkers present in the urine.

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