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Randomized clinical trial of direct restorations of non-carious cervical lesions using a universal adhesive and surface pretreatment

Grant number: 22/09366-7
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): May 01, 2023
Field of knowledge:Health Sciences - Dentistry - Dental Clinics
Principal Investigator:Ana Cecília Corrêa Aranha
Grantee:Mirian Lumi Yoshida
Host Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil


This in vivo study aims to evaluate the longevity of restorations in NCCLs abraded with aluminum oxide particles, using two adhesive systems, based on a double-blind randomized clinical study. The experimental groups will be: G1: air-abrasion with aluminum oxide at 50 mm + Single Bond Universal adhesive (3M Oral Care) with selective enamel etching; G2: Single Bond Universal (3M Oral Care) with selective enamel etching; G3: air-abrasion with 50 mm aluminum oxide + Universal Single Bond (3M Oral Care) with enamel and dentin conditioning; G4: Single Bond Universal (3M Oral Care) with enamel and dentin conditioning. An initial assessment and screening of patients will be performed at the Special Laboratory of Laser in Dentistry, Faculty of Dentistry, University of São Paulo (LELO-FOUSP), according to the inclusion and exclusion criteria. The selected participants will be informed about the research and will fill out the Free and Informed Consent Form and an anamnesis form. An envelope will be opened according to the randomization sequence to define the group treatment to be applied, on each tooth (premolar or molar with NCCL of at least 1 mm in length and depth). After application of the adhesive system, the teeth will be restored with Filtek Z350 XT resin (3M Oral Care, USA), using the direct technique. The restorations will be evaluated by 2 researchers calibrated according to some criteria of the FDI (FDI World Dental Federation) for clinical evaluation of direct restorations. Evaluations will be made in the periods of 1 week, 6, 12, 24 months after the completion of the restorations. For all groups, the data obtained at all times will be subjected to statistical analysis by Kruskall Wallis to compare treatments after each study period with a significance level of 5%. The Friedman test will be used to determine differences in the rates of each group in all periods. The results will also be analyzed through annual survival rates (Kaplan-Meier). (AU)

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