Scholarship 23/03760-8 - Bactérias, Fungos - BV FAPESP
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BIOSYNTHESIS AND CHARACTERIZATION OF SILVER NANOPARTICLES USING STRYPHNODENDRON ADSTRINGENS PLANT EXTRACT AND ASSESSMENT OF ITS BIOLOGICAL POTENTIAL

Grant number: 23/03760-8
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Start date until: May 01, 2023
End date until: July 01, 2024
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal Investigator:Ljubica Tasic
Grantee:Maelson Cardoso Lacerda
Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

With the discovery of nanoparticles, biotechnology products containing silver(0) have been used for a wide variety of purposes, such as fighting bacteria, fungi, treating wounds, burns, infections, and for use in medical and hospital supplies that affect a wide variety of pathogens. The silver nanoparticles (AgNPs) incorporated into the various types of products act as a reservoir for the continuous, controlled release of silver ions, thus achieving greater efficiency in the proposed treatment. Nanoparticles can be obtained using organic or inorganic reducing agents that reduce silver ions to metallic silver. However, the use of these chemical reagents and solvents usually makes these methods labor-intensive, expensive, and produces toxic waste, especially to the environment. An alternative is the green synthesis, which uses biological media or plant extracts to reduce the ion (Ag+) to its metallic form(Ag0). The synthesis of AgNPs using plant extracts reduces the use of chemical reducingagents, since this biological method involves the use of plant extracts containing molecules capable of reducing metal ions to AgNPs in a single step. The advantage of this method for the chemical one is that plants produce functional biomolecules that reduce metal ions and adhere to the surface of these nanoparticles, giving them several properties, such as protection and stability, besides high efficiency, environmental sustainability and low production cost. Therefore, more sustainable alternatives - both financially and/or environmentally - should be considered and studied. Thus, the aim of the current project isthe biosynthesis and characterization of silver nanoparticles using extracts from the plantStryphnodendron astringens and evaluation of its biological potential.

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