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Development of a low cost high entropy alloy for potential use as bone fixation devices

Grant number: 21/13921-3
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): December 01, 2022
Status:Discontinued
Field of knowledge:Engineering - Materials and Metallurgical Engineering - Physical Metallurgy
Principal Investigator:Diego Rafael Nespeque Correa
Grantee:Jhuliene Elen Muro Torrento
Host Institution: Faculdade de Ciências (FC). Universidade Estadual Paulista (UNESP). Campus de Bauru. Bauru , SP, Brazil
Associated scholarship(s):23/15812-2 - Development of a novel high entropy alloy by mechanical alloying, BE.EP.DR

Abstract

In recent years, high entropy alloys (HEAs) composed of 5 or more elements in a proportion close to equimolar have been developed. These materials have been recognized for their high mechanical strength, ductility, and corrosion resistance, which have attracted attention in the biomedical field. However, the currently developed high entropy alloys do not have adequate mechanical, electrochemical, and biological properties for use as biomaterials. This makes the development of new HEA alloys for use specifically as biomaterials a promising field. In addition, surface modification methods, including plasma electrolytic oxidation (PEO), has been proven to be useful to accelerate the process of osseointegration and bone tissue recovery, in addition to preventing bacterial infection on the implant surface. However, the study of surface treatment by PEO in HEA alloys is still incipient, having the potential to bring interesting results for the application. This project aims to develop a novel high entropy alloy, composed of non-toxic, low cost, and low melting point elements, such as Ti, Zr, Mn, Al, and Fe, for potential use in biomedical application, such as bone fixation devices (pins, plates, and screws), which require unique properties to fix and hold bone tissue together. The surface of the alloys will be modified by PEO to produce surfaces with biofunctional properties, such as biocompatibility, osseointegration, and bioactivity.

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