Scholarship 21/13799-3 - Ciclismo, Eficiência - BV FAPESP
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Gender differences in the performance response of trained cyclists on a 4-km cycling time trial after inorganic nitrate supplementation

Grant number: 21/13799-3
Support Opportunities:Scholarships in Brazil - Master
Start date until: November 01, 2022
End date until: October 31, 2024
Field of knowledge:Health Sciences - Nutrition
Principal Investigator:Bryan Saunders
Grantee:Arthur Amaral de Carvalho
Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

There is good evidence that nitrate supplementation can improve exercise performance and capacity in male individuals. However, women are clearly underrepresented in nitrate supplementation research and a substantial proportion of studies with this population shows no effects with the use of this supplement. Nevertheless, there is also evidence to the contrary, suggesting that nitrate may benefit the performance of female athletes. It is possible that the lack of benefit from nitrate intake, in many of the investigations conducted with women, is due to sub-optimal aspects in their study designs. Furthermore, to date, no study has directly compared the performance response to nitrate supplementation between men and women. Therefore, this study will investigate whether acute nitrate supplementation is as effective in improving exercise performance in women as in men using a study design that is conducive to demonstrate the ergogenic effect of nitrate supplementation. Thirty trained cyclists (15 men and 15 women) will perform a 4-km cycling time-trial in a double-blind, crossover, counterbalanced and randomized model, two and a half hours following supplementation with 70 ml of concentrated beetroot juice containing 6.2 mmol of nitrate (NIT), 70 ml of nitrate-free concentrated beetroot juice (PLA) or a non-placebo control (CON). This study will be the first to directly compare the performance response to nitrate intake between men and women, controlling oral hygiene practices and using supplementation and exercise protocols that are likely to demonstrate an ergogenic effect should it exist. The results of this study will be of great relevance to female athletes who are looking for strategies to improve sports performance and may impact the design of future studies.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CARVALHO, ARTHUR; DUARTE, BRENO; ELLIOTT-SALE, KIRSTY JAYNE; SAUNDERS, BRYAN. Directions for Future Studies to Determine Dietary Nitrate Efficacy in Female Athletes. TRANSLATIONAL JOURNAL OF THE AMERICAN COLLEGE OF SPORTS MEDICINE, v. 8, n. 4, p. 3-pg., . (21/06836-0, 21/13799-3, 16/50438-0, 19/06140-5)

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