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SARCOPENIC OBESITY AND ASSOCIATIONS WITH MUSCLE STRENGTH AND PHYSICAL PERFORMANCE IN PHYSICALLY ACTIVE OLDER ADULTS

Grant number: 22/07280-8
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): September 01, 2022
Effective date (End): August 31, 2023
Field of knowledge:Health Sciences - Physical Education
Principal Investigator:Dalmo Roberto Lopes Machado
Grantee:Leonardo Santos Lopes da Silva
Host Institution: Escola de Educação Física e Esporte de Ribeirão Preto (EEFERP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

Sarcopenic obesity (SO) is a clinical and functional condition characterized by the coexistence of reduced skeletal muscle mass and excess fat mass (obesity), with a higher incidence risk during aging. This condition impacts muscle strength (MS) (sarcopenia) and physical performance (PP) (severe sarcopenia), increasing the risk of falls, hospitalizations, and premature mortality in older adults. Literature advises adequate indices of moderate/vigorous physical activity (WHO, 2010) for attenuating the risk of SO, although these conditions do not exempt older adults from this risk. Furthermore, the thresholds of morpho-functional losses do not yet know. Thus, we aim to determine the risk thresholds of SO from reduced MS and PP, even if in older physically active adults. An established statistical sample of ninety-four older adults enrolled in regular physical activity programs is involved in this study. SO diagnosis will be confirmed when the older adult presents low muscle mass (masc. [ALST< 19,75kg]; fem. [ALST <15,02]) and high fat % (masc. e 25%; fem. e35%). The MS (knee extension in an isokinetic dynamometer, extensor chair, and handgrip) and PP (6-minute walking test, gait speed, and time up and go) are comparative parameters between groups (independent samples t-test). The explanatory variability of MS and PP (multiple linear regression) and odds ratio for the risk of SO (binary logistic regression) will be determined, considering the adjustment by the block of confounding variables (sociodemographic characteristics, nutritional status, amount of drugs ingested, and health risk behaviors). Thus, the risk thresholds of SO in older physically active adults will be known.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DA SILVA, LEONARDO SANTOS LOPES; ABDALLA, PEDRO PUGLIESI; BOHN, LUCIMERE; ARAUJO, RAFAEL GAVASSA DE; BATALHAO, DANIEL DE FREITAS; VENTURINI, ANA CLAUDIA ROSSINI; CARVALHO, ANDERSON DOS SANTOS; DUNCAN, MICHAEL; MOTA, JORGE; MACHADO, DALMO ROBERTO LOPES. Association of minimally processed and ultra-processed food daily consumption with obesity in adults: a cross-sectional study. NUTRICION HOSPITALARIA, v. 40, n. 3, p. 9-pg., . (22/07280-8)
DA SILVA, LEONARDO SANTOS LOPES; GONCALVES, LEONARDO DA SILVA; ABDALLA, PEDRO PUGLIESI; BENJAMIM, CICERO JONAS RODRIGUES; TASINAFO JR, MARCIO FERNANDO; VENTURINI, ANA CLAUDIA ROSSINI; BOHN, LUCIMERE; MOTA, JORGE; MARCOS-PARDO, PABLO JORGE; KEMMLER, WOLFGANG; et al. Characteristics of resistance training-based protocols in older adults with sarcopenic obesity: a scoping review of training procedure recommendations. FRONTIERS IN NUTRITION, v. 10, p. 15-pg., . (22/07280-8)
DA SILVA, LEONARDO SANTOS LOPES; TASINAFO JUNIOR, MARCIO FERNANDO; GONCALVES, LEONARDO DA SILVA; DA SILVA, ARTHUR POLVEIRO; LEITE, LUIS FELIPE PENGO ALMEIDA; FAVERO, LAURA SCATENA; BARDELLA, MATEUS DO CARMO; DE LIMA, JOAO GABRIEL RIBEIRO; BUENO JUNIOR, CARLOS ROBERTO; DE MORAES, CAMILA. Does Multicomponent Training Improve Cognitive Function in Older Adults Without Cognitive Impairment? A Systematic Review and Meta-Analysis of Randomized Controlled Trials. JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, v. 24, n. 6, p. 8-pg., . (22/07280-8)

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