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Oxygen saturation in the nutritive suction of breast milk in children with isolated Robin sequence: an analysis by means of high resolution oximetry

Grant number: 21/10425-5
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): December 01, 2021
Effective date (End): July 31, 2022
Field of knowledge:Biological Sciences - Physiology - Physiology of Organs and Systems
Principal Investigator:Ivy Kiemle Trindade Suedam
Grantee:Clara Maria Santos Wanderley
Host Institution: Hospital de Reabilitação de Anomalias Craniofaciais (HRAC). Universidade de São Paulo (USP). Bauru , SP, Brazil


The Robin Sequence (SR) consists of a triad of anomalies, characterized by micrognathia, glossoptosis, and, in most cases, cleft palate (SATO et al. 2007). In relation to breastfeeding, the child with RS is unable to perform adequate sucking and swallowing due to the presence, above all, of micrognathia and cleft palate. Both factors cause incoordination between sucking and swallowing and favor partial resistance to breathing. Objective: To evaluate oxygen saturation during breastfeeding in children with Isolated Robin Sequence in the 0 to 6 month age group, using high-resolution oximetry. Method: Participants will be divided into two groups: the breastfeeding group and the bottle feeding group. In both, the following factors will be evaluated: oxygen saturation during breastfeeding, using the Oxistar BX1 oximeter, and the practices adopted by mothers related to baby nutrition, through the application of questionnaires. Data collection will be carried out at the Hospital for Craniofacial Anomalies (HRAC-USP), in the period of F and G of 2021.Expected results: It is our hypothesis that during breastfeeding in babies with Robin Sequence, more specifically in nutritional suction, there is a sharp drop in oxygen saturation, due to the association of two factors: micrognathia and cleft palate. The first, in this case, causes abnormal implantation of the tongue, which assumes a retroposition (glossoptosis) favoring a partial resistance to breathing. The second, when present, makes it impossible to create negative intraoral pressure, necessary for suction. (AU)

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