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Effect of a new bleaching agent formulation containing sodium trimetaphosphate nano-sized on dental enamel

Grant number: 21/07338-3
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): October 01, 2021
Effective date (End): September 30, 2023
Field of knowledge:Health Sciences - Dentistry - Dental Materials
Principal Investigator:Alberto Carlos Botazzo Delbem
Grantee:Mariana Takatu Marques
Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil

Abstract

The objective of this study will be to evaluate in vitro a new bleaching agent containing nanoparticles of Sodium trimetaphosphate (TMP) associated with sodium fluoride (F) and 17.5% hydrogen peroxide about aesthetic effectiveness, surface hardness, and roughness of tooth enamel. The whitening gels will be applied on bovine tooth discs, according to the groups: 1) 17.5% hydrogen peroxide (17.5% H2O2); 2) H2O2 + 0.1% NaF (H2O2/F); 3) H2O2 + 1% TMP nano (H2O2/TMP); 4) H2O2 + 0.1%NaF + 1% TMP nano (H2O2/F/TMP) and 5) 35% hydrogen peroxide (35% H2O2). the whitening gel will be applied once in 3 sessions of 7 days each, after the treatment period the change will be evaluated(at different times) by quantified reflection spectrophotometry. It will also be determined the initial and after treatment (final) surface hardness, and the roughness of the dental enamel before and after the bleaching procedure. Variables that present normal and homogeneous distribution will be submitted to analysis of variance (p<0.05). Otherwise, they will be submitted to the Kruskal Wallis test (p<0.05). The multiple comparison test will be Student-Newman-Keuls. (AU)

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