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Evaluation of the physical-mechanical properties of a glass ionomer cement modified by zinc oxide nanoparticles and calcium glycerophosphate microparticles: in vitro study

Grant number: 21/06411-9
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): October 01, 2021
Effective date (End): February 28, 2023
Field of knowledge:Health Sciences - Dentistry - Pediatric Dentistry
Principal Investigator:Marcelle Danelon
Grantee:Maria Fernanda Cavalcante Meira
Host Institution: Universidade de Ribeirão Preto (UNAERP). Campus Ribeirão Preto. Ribeirão Preto , SP, Brazil


Dental caries is a multifactorial, biofilm-sugar-dependent disease. The use of calcium releasing agents and nanoparticles has aroused great interest in the optimization of products aimed at controlling the disease, in order to increase their anticaries potential and thus restore oral health to the individual. This study aims to evaluate the effect of incorporation of zinc oxide nanoparticles (ZnONPs) and calcium glycerophosphate microparticles (CaGP) in resin-modified glass ionomer cement (RGIC) on their physical-mechanical properties. Specimens of each material (n=6) will be made: 1) CIVMR without ZnONPs/CaGP (Control); 2) CIVMR with 1.0% ZnONPs; 3) CIVMR with 2.0% ZnONPs; 4) CIVMR with 3.0% CaGP; 5) CIVMR with 1.0% ZnONPs and 3.0% CaGP and 6) CIVMR with 2.0% ZnONPs, (% m/m). The physical-mechanical properties of the CIVMR will be determined: Diametric tensile strength, Compressive strength, Material hardness, and Surface roughness. For statistical analysis, the values of the physical-mechanical tests will be considered as variables (diametrical traction - kgF/cm2, Compression - MPa, hardness of materials - KHN and surface roughness - RS). The data will be submitted to normality and homoscedasticity tests to apply the statistical analysis best suited to the data distribution. The statistical program Sigmaplot® for Windows version 12.0 will be used, with significance at the 5% level. (AU)

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