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Effect of the ephaptic coupling on neural networks dynamics

Grant number: 20/16389-8
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): May 01, 2021
Effective date (End): April 30, 2022
Field of knowledge:Interdisciplinary Subjects
Principal Investigator:Marcelo Bussotti Reyes
Grantee:Angelo Orletti Del Rey
Host Institution: Centro de Matemática, Computação e Cognição (CMCC). Universidade Federal do ABC (UFABC). Ministério da Educação (Brasil). Santo André , SP, Brazil


During regular brain activity, charge transfer between neurons gives rise to extracellular electric potential in neural tissue. These electric fluctuations can disrupt neighbor cells' activity, acting as a non-synaptic connection between neurons, called ephaptic coupling. Even though known for decades, ephaptic coupling effects still need to be quantified, particularly in large structures like the cortex. In this project, we will use computational modeling of neuronal networks to investigate the effects of ephaptic coupling in neural networks dynamics.

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