Inhibitory Deficit as a Marker of Neuroplasticity in Rehabilitation - Knowledge Translation

Abstract

The "Inhibitory Deficit as a Marker of Neuroplasticity in Rehabilitation" is a hypothesis-based project and aims to identify neurophysiological biomarkers of functional recovery in four different clinical conditions in a "transdiagnostic" approach, namely stroke, spinal cord injury, amputation and knee osteoarthritis. These conditions will be compared to healthy individuals (matched for age and gender). The project foresees the collection of clinical, demographic, functional and neurophysiological data from 500 participants (400 patients (100 for each disease group) + 100 healthy controls) through a period of four years. It is hoped that the knowledge obtained from this project might be used to guide protocols and planning of rehabilitation therapies. Therefore, the goal of the post-doc student will be to use the biomarkers identified in the study to propose new rehabilitation protocols for stroke and spinal cord injury patients.