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Understanding and managing resistance, including novel methods, for pathogen and pest control

Grant number: 20/07806-4
Support Opportunities:Scholarships in Brazil - Post-Doctoral
Effective date (Start): September 01, 2020
Effective date (End): October 31, 2021
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Acordo de Cooperação: BBSRC, UKRI ; Newton Fund, with FAPESP as a partner institution in Brazil
Principal Investigator:Maria Fátima das Graças Fernandes da Silva
Grantee:Daniel Petinatti Pavarini
Host Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
Associated research grant:18/21201-8 - Novel delivery of phytochemicals for sustainable crop protection, AP.R


The Stage 2 (BBSRC-FAPESP) project will use the collaboration established in Stage 1 to move towards generating new commercially viable phytochemical treatments. Experimental work will focus on three main areas: 1) Development and optimisation of phytochemical delivery using nanoformulation and complexing techniques. Treatments will be scaled up from leaf discs to whole plants with detailed investigation of two promising routes for application: sprayable formulations and systemic uptake via root drench treatments. 2) Testing bioactivity of formulations against economically important Brazilian crop pest targets. Antibiotic, antifeedant and repellent activity will be tested for using established methods we have developed. 3) Environmental and target specificity assessment. Most of the phytochemicals and formulations we are testing are already widely used as food ingredients, in medicine or in aromatherapy. However, we will obtain evidence in order to make the case for subsequent commercialisation of treatments. Breakdown of new biodegradable formulations will be measured. Non-target effects will be assessed with mammalian cell lines, an egg parasitoid wasp Trichogramma pretiosum, a beneficial natural enemy, and the honeybee, Apis mellifera.BBSRC-FAPESP (AU)

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