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Effects of different types of carbohydrates during exercise on performance and metabolic responses

Grant number: 19/07497-4
Support type:Scholarships in Brazil - Master
Effective date (Start): July 01, 2020
Effective date (End): January 31, 2022
Field of knowledge:Health Sciences - Physical Education
Principal researcher:Bryan Saunders
Grantee:Nathan Gobbi de Oliveira
Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil


The objective of this project is to investigate the ergogenic effects of trehalose supplementation throughout prolonged cycling in trained cyclists. Acting as controls, we will use a conventional placebo (sweetener), maltodextrin (carbohydrate with high glycaemic index) and isomaltose (carbohydrate with low glycaemic index), these two being considered as positive controls. Our hypothesis is that supplementation of trehalose will have equivalent effects or greater than supplementation of maltodextrin and isomaltose, with all three carbohydrates more efficient than the placebo for performance. Twelve male cyclists between 18 and 40 years, with previous experience in cycling will be recruited to take part in this project. The study will have a cross-over, counterbalanced, double-blind design and controlled by placebo. There will be four conditions as follows: (a) Placebo (b) Maltodextrin (c) Isomaltose and (d) Trehalose. The latin square techinique will determine the sequence of the tests. The supplements will be ingested during the physical activity, ingesting 200 ml each 20 min throughout. The exercise test will be performed on a cycle ergometer and will comprise of 120 min cycling 100 min of intermittent exercise followed by a 20 min time-trial test. Performance will be evaluated as the total work produced (kJ) and the total distance covered (km) during the time-trial. Blood tests will be taken every 20 min during the exercise for blood glucose, nitrate and nitrite. Muscular biopsies will be realized before and immediately after each session, and subsequently analysed for muscle glycogen. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
PERIM, PEDRO; GOBBI, NATHAN; DUARTE, BRENO; FARIAS DE OLIVEIRA, LUANA; COSTA, LUIZ AUGUSTO RIANI; SALE, CRAIG; GUALANO, BRUNO; DOLAN, EIMEAR; SAUNDERS, BRYAN. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. European Journal of Sport Science, . (19/07497-4, 17/13552-2, 18/01594-5, 19/06140-5, 16/17391-0, 16/50438-0, 19/05616-6)

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