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Mathematical modelling of the Wheatley heart valve

Grant number: 20/02581-4
Support type:Scholarships in Brazil - Post-Doctorate
Effective date (Start): September 01, 2020
Effective date (End): August 31, 2021
Field of knowledge:Physical Sciences and Mathematics - Mathematics - Applied Mathematics
Principal researcher:José Alberto Cuminato
Grantee:Ramiro James Rebolledo Cormack
Home Institution: Instituto de Ciências Matemáticas e de Computação (ICMC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
Associated research grant:13/07375-0 - CeMEAI - Center for Mathematical Sciences Applied to Industry, AP.CEPID


This project is a proof-of-concept of a novel aortic valve for the human heart. It involves mathematical modelling spiral and pulsatile blood flow from the left ventricle into and through an artificial heart valve. The valve has three leaflets (or flaps) which open and close in accordance with systole and diastole. These large (elastic) deflections, driven by the pressure gradient of the blood, need to be modelled and numerically simulated in order to ensure that the valve opens and closes rapidly and the shear stress in the blood flow is always above a critical limit to avoid blood clotting. A comparison with the standard current state-of-the-art valve will be undertaken. (AU)

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