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Healthy lifestyle promotion in patients with Systemic Lupus Erythematosus: effects on life quality and psychological aspects

Grant number: 19/14820-6
Support Opportunities:Scholarships in Brazil - Doctorate (Direct)
Effective date (Start): March 01, 2020
Effective date (End): February 29, 2024
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal Investigator:Bruno Gualano
Grantee:Bruna Caruso Mazzolani
Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil


Systemic Lupus Erythematosus patients have a lower health-related quality of life when compared to the general population and also to other rheumatic and severe chronic diseases. Disease activity, pain, fatigue, treatment, comorbidities, demographic, social and emotional factors are predictors of a lower life quality in these patients. In theory, interventions to promote physical activity and health food consumption could improve life quality of Systemic Lupus Erythematous patients. This large randomized controlled trial ("Living Well with Lupus") aims to evaluate the effects of a new "real world" clinic intervention, that promotes structured and unstructured physical activity and health food consumption (based on Dietary Guideline for the Brazilian population), on cardiovascular risk, life quality, sleep quality and psychological aspects in Systemic Lupus Erythematous patients. In this thesis, specifically, the outcomes of interest are the ones associated with life quality, sleep quality and psychological aspects. Quantitative and qualitative methods will be used. Before and after intervention, will be evaluated: 1) physical activity level and sedentary behavior; 2) food consumption; 3) clinical parameters; 4) life quality; 5) psychological aspects (anxiety, depression); 6) sleep quality. Focus groups will be performed at the end of the follow-up to qualitatively evaluate intervention impacts. The findings of this project can fit as base for new prescriptions based in evidence with the aim to modify Systemic Lupus Erythematous patients life style. (AU)

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Scientific publications (6)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
SMAIRA, FABIANA INFANTE; MAZZOLANI, BRUNA CARUSO; ESTEVES, GABRIEL PERRI; ANDRE, HELOISA C. SANTO; AMARANTE, MILLA CORDEIRO; CASTANHO, DANIELA FERNANDES; CAMPOS, KAREN JENNIFER DE; BENATTI, FABIANA BRAGA; PINTO, ANA JESSICA; ROSCHEL, HAMILTON; et al. Poor Eating Habits and Selected Determinants of Food Choice Were Associated With Ultraprocessed Food Consumption in Brazilian Women During the COVID-19 Pandemic. FRONTIERS IN NUTRITION, v. 8, . (19/14819-8, 20/07860-9, 17/13552-2, 15/26937-4, 19/14820-6)
SIECZKOWSKA, MENDES; SMAIRA, FABIANA INFANTE; MAZZOLANI, BRUNA CARUSO; GUALANO, BRUNO; ROSCHEL, HAMILTON; PECANHA, TIAGO. Efficacy of home-based physical activity interventions in patients with autoimmune rheumatic diseases: A systematic review and meta-analysis. SEMINARS IN ARTHRITIS AND RHEUMATISM, v. 51, n. 3, p. 576-587, . (19/07150-4, 19/14820-6, 17/13552-2, 16/23319-0, 19/14819-8, 19/15231-4)
MAZZOLANI, BRUNA CARUSO; SMAIRA, FABIANA INFANTE; ESTEVES, GABRIEL PERRI; SANTO ANDRE, HELOISA C.; AMARANTE, MILLA CORDEIRO; CASTANHO, DANIELA; CAMPOS, KAREN; BENATTI, FABIANA BRAGA; PINTO, ANA JESSICA; ROSCHEL, HAMILTON; et al. Influence of Body Mass Index on Eating Habits and Food Choice Determinants Among Brazilian Women During the COVID-19 Pandemic. FRONTIERS IN NUTRITION, v. 8, . (20/07860-9, 17/13552-2, 15/26937-4, 19/14819-8, 19/14820-6)
PINTO, ANA J.; MEIRELES, KAMILA; PECANHA, TIAGO; MAZZOLANI, BRUNA C.; SMAIRA, I, FABIANA; REZENDE, DIEGO; BENATTI, FABIANA B.; RIBEIRO, ANA C. M.; PINTO, ANA L. S.; LIMA, FERNANDA R.; et al. Acute cardiometabolic effects of brief active breaks in sitting for patients with rheumatoid arthritis. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, v. 321, n. 6, p. E782-E794, . (19/14819-8, 19/14820-6, 17/13552-2, 16/23319-0, 15/26937-4, 18/19418-9)
MAZZOLANI, BRUNA CARUSO; SMAIRA, FABIANA INFANTE; ASTLEY, CAMILLA; IRAHA, AMANDA YURI; PINTO, ANA JESSICA; MARQUES, ISABELA GOUVEIA; CORDEIRO AMARANTE, MILLA; REZENDE, NATHALIA SAFFIOTI; SIECZKOWSKA, SOFIA MENDES; FRANCO, TATHIANE CHRISTINE; et al. Changes in Eating Habits and Sedentary Behavior During the COVID-19 Pandemic in Adolescents With Chronic Conditions. FRONTIERS IN PEDIATRICS, v. 9, . (19/20814-9, 19/14819-8, 19/14820-6, 16/00006-7, 17/13552-2, 19/15231-4, 15/03756-4, 15/26937-4)
ISABELA GOUVEIA MARQUES; CAMILLA ASTLEY; SOFIA MENDES SIECZKOWSKA; AMANDA YURI IRAHA; TATHIANE CHRISTINE FRANCO; FABIANA INFANTE SMAIRA; BRUNA CARUSO MAZZOLANI; LUANA CRISTINA DO AMARAL MIRANDA; BIANCA PIRES IHARA; ROSA MARIA R. PEREIRA; et al. Lessons learned from a home-based exercise program for adolescents with pre-existing chronic diseases during the COVID-19 quarantine in Brazil. Clinics, v. 76, . (16/00006-7, 19/15231-4, 15/03756-4, 19/14819-8, 19/20814-9, 19/14820-6, 17/13552-2)

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