Advanced search
Start date

Studies of the differential expressed immune genes in organs of ornamental fish in response to myxosporeans infection

Grant number: 19/13147-6
Support Opportunities:Scholarships abroad - Research Internship - Post-doctor
Effective date (Start): November 01, 2019
Effective date (End): October 31, 2020
Field of knowledge:Biological Sciences - Zoology - Morphology of Recent Groups
Principal Investigator:André Carrara Morandini
Grantee:Patrick Mathews Delgado
Supervisor: Fabienne Audebert
Host Institution: Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Research place: Université Paris-Sorbonne (Paris 4), France  
Associated to the scholarship:18/20482-3 - Diversity of microscopic cnidarians from the Amazon Basin with emphasis on phylogeny, systematic and interaction with their hosts, BP.PD


In the original project it was planned the accomplishment of part of the research in a center of excellence abroad. Therefore, with this research project we aim to increment and develop studies of molecular mechanisms involved in immune defense of fish against myxosporeans, increasing knowledge and competences, besides acquiring new expertizes, regarding the Postdoctoral project in execution. Studies performed so far, have shown a large number of new myxosporeans species infecting Amazonian ornamental fish, as well as different host response to the presence of these parasites were found during our recent research. In this project, studies of identification and evaluation of the expression of immune genes in fishes infected with myxosporean parasites will contribute to elucidate the molecular mechanisms involved in immune defense of hosts in response to myxosporeans infection. In the same way, this project aims to identify and determine the patterns of immune gene expression in fishes infected by myxosporean parasites. Finally, considering that studies about characterization of the fish immune gene system and its regulation is crucial for the development of vaccines and other preventive measures such as immunomodulation and selection of disease-resistant strains, this project will be of great importance for the progress of strategies to better prevent future disease outbreaks in wild and farmed freshwater fish.

News published in Agência FAPESP Newsletter about the scholarship:
Articles published in other media outlets (0 total):
More itemsLess items

Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MATHEWS, PATRICK D.; MERTINS, OMAR; ANGELOV, BORISLAV; ANGELOVA, ANGELINA. Cubosomal lipid nanoassemblies with pH-sensitive shells created by biopolymer complexes: A synchrotron SAXS study. Journal of Colloid and Interface Science, v. 607, n. 1, p. 440-451, . (19/13147-6, 21/00971-2, 18/21727-0)
MERTINS, OMAR; MATHEWS, PATRICK D.; ANGELOVA, ANGELINA. Advances in the Design of pH-Sensitive Cubosome Liquid Crystalline Nanocarriers for Drug Delivery Applications. NANOMATERIALS, v. 10, n. 5, . (16/13368-4, 19/13147-6, 18/21727-0)
MILANIN, TIAGO; MATHEWS, PATRICK D.; MORANDINI, ANDRE C.; MERTINS, OMAR; AUDEBERT, FABIENNE; PEREIRA, JOSE O. L.; MAIA, ANTONIO A. M.. Morphostructural data and phylogenetic relationships of a new cnidarian myxosporean infecting spleen of an economic and ecological important bryconid fish from Brazil. Microbial Pathogenesis, v. 150, . (15/21007-9, 19/13147-6, 18/20482-3, 15/18807-3)
MATHEWS, PATRICK D.; BONILLO, CELINE; RABET, NICOLAS; LORD, CLARA; CAUSSE, ROMAIN; KEITH, PHILIPPE; AUDEBERT, FABIENNE. Phylogenetic analysis and characterization of a new parasitic cnidarian (Myxosporea: Myxobolidae) parasitizing skin of the giant mottled eel from the Solomon Islands. INFECTION GENETICS AND EVOLUTION, v. 94, . (18/20482-3, 19/13147-6)

Please report errors in scientific publications list by writing to: